Suppose that α1,α2,β1,β2∈ℝ. Let α1,α2>1 be irrational and of finite type such 1,α1−1,α2−1 are linearly independent over ℚ. c a real number in the range 1<c<12∕11. In this paper, it is proved there exist infinitely many primes intersection Beatty sequences ℬα1,β1=⌊α1n+β1⌋, ℬα2,β2=⌊α2n+β2⌋ Piatetski-Shapiro sequence

Caspian kutum, Rutilus frisii kutum, is one of the most commercially important fish species in the Caspian Sea, but there are few reports about the endocrinology of induced spawning in this fish. In the present study, 54 individuals of female broodstocks of Kutum were studied for quantity and quality of propagation index, during March and April 2007. Hormone treatments include: LHRH-A2 (1 ?g kg...

The present study was aimed to examine the possible functional relationship between melatonin and hypothalamic transmitters, endogenous opioids and excitatory amino acids in controlling gonadotropin secretion in ovariectomized estrogen-primed rats. An intravenous injection of naloxone (mu opioid receptor antagonist), N-methyl-D-aspartate (NMDA; NMDA receptor agonist) or luteinizing hormone-rele...

The luteinizing hormone-releasing hormone (LHRH) agonist ICI 118630 was found to increase testosterone production in purified rat testis Leydig cells in a concentration- and time-dependent manner, but no consistent changes in cyclic AMP levels were detectable. The stimulation of steroidogenesis by LHRH agonist was found to be dependent on the concentration of Ca2+ in the incubation medium; at l...

The ovary is the major site of oestrogen production in premenopausal women. Removal of the ovaries in premenopausal patients with breast cancer has long been recognised to potentially alter the course of disease. This procedure leads to a marked reduction in the circulating levels of oestrogen. It has been shown that ovariectomy given as an adjuvant treatment reduces the odds of recurrence or d...

To assess changes of gonad development and sex steroids hormones of R. frisii kutum, broodfish were captured during spawning season 2010 (March-April) and induced intramuscularly with following hormone treatments: single injections of 1 μg kg b.w. LHRH-A2, combination of LHRH-A2 with two dopamine antagonists as follows: 1 μg kg b.w. LHRH-A2 + 5 mg kg-1 b.w. PIM, 1 μg kg b.w. LHRH-A2 + 2.5 mg kg...

Objectives: The aim of this study was to examine the efficacy and toxicity between luteinising hormone releasing hormone analogue (LHRH-a) therapy and maximal androgen blockade (MAB) therapy in patients with advanced prostate cancer in China. Materials and methods: A total of 392 patients with advanced prostate cancer were included in the study. Patients who received LHRH-a therapy were include...

Previous reports demonstrate that the α2-integrin (α2) mediates pancreatic ductal adenocarcinoma (PDAC) cell interactions with collagens. We found that while well-differentiated cells use α2 exclusively to adhere and migrate on collagenI, poorly differentiated PDAC cells demonstrate reduced reliance on, or complete loss of, α2. Since well-differentiated PDAC lines exhibit reduced in vitro invas...

A male patient with hypogonadotropic hypogonadism has been treated by pulsatile administration lf luteinizing hormone-releasing hormone (LHRH) (20-25 micrograms, every 2 hours, sc) for 4 years 6 months. His plasma testosterone (T) concentration began to increase after 4 weeks of treatment and reached the normal range in week 5. He showed complete secondary sexual development after 1 year of tre...