OBJECTIVE This prospective study examined the convergent validity and responsiveness of the EuroQoL-5 Dimensions Health Questionnaire (EQ-5D) utility weights in stroke survivors at the subacute stage. METHODS Repeated assessments were conducted in rehabilitation wards of a medical centre. A study cohort was recruited from inpatients (n = 478). A total of 342 participants (71.5%) completed 2 a...

BACKGROUND Diabetes is a major health problem in Korea. However, interest in the quality of life in patients with diabetes is low. We examined the effects of diabetes on health-related quality of life (HRQoL) and compared it with HRQoL in the general Korean population using the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) (2007-2009). METHODS Using KNHANES IV dat...

OBJECTIVE To estimate quality weights of EQ-5D health states with the time trade-off (TTO) method in the general population of South Korea. METHODS A total of 500 respondents valued 42 hypothetical EQ-5D health states using the TTO and visual analog scale. The quality weights for all EQ-5D health states were estimated by a random effects model and compared with those from studies in other cou...

Acknowledgements: We thank Aki Tsuchiya, John Brazier and Ben van Hout for helpful comments and advice and Jenny Dunn for formatting the report. The content of this report is the responsibility of the authors alone. 2 SUMMARY Economic evaluation is an important component for decision making, underpinning much of the guidance issued by NICE. Typically these economic evaluations have taken the fo...

BACKGROUND The EQ-5D is frequently used to derive utilities for patients with type 2 diabetes (T2D). Despite widely available quantitative psychometric data on the EQ-5D, little is known about content validity in this population. Thus, the purpose of this qualitative study was to examine content validity of the EQ-5D in patients with T2D. METHODS Patients with T2D in the UK completed concept ...

INTRODUCTION Patients with moderate-to-severe atopic dermatitis (AD) report a multidimensional disease burden that includes impaired health-related quality-of-life (HRQoL). Changes in overall health status and specific dimensions that contribute to HRQoL were evaluated in adults with moderate-to-severe AD who participated in phase 3 clinical trials of dupilumab, which is a fully human monoclona...