After an acute low thoracic spinal transection (T13), cats can be made to walk with the hindlimbs on a treadmill with clonidine, an alpha2-noradrenergic agonist. Because previous studies of neonatal rat spinal cord in vitro suggest that the most important lumbar segments for rhythmogenesis are L1-L2, we investigated the role of various lumbar segments in the initiation of walking movements on a...

Abstract Background Sarcopenia is increasingly recognised to impact the quality of life and patient outcomes. The relationship with brain frailty unknown. Objectives Assess if muscle mass at C3 correlates L3 on routine trauma imaging. for associations between muscle-mass, brain-frailty, Clinical Frailty Scale (CFS) Method Routine trauma-series CT scans were retrospectively analysed patients age...

Six silver(I) coordination complexes have been prepared and structurally characterised. Mixed chalcogen-donor acenaphthene ligands L1-L3 [Acenap(EPh)(E'Ph)] (Acenap = acenaphthene-5,6-diyl; E/E' = S, Se, Te) were independently treated with silver(I) salts (AgBF₄/AgOTf). In order to keep the number of variables to a minimum, all reactions were carried out using a 1:1 ratio of Ag/L and run in dic...

Transfer phenomena in Italian L3 by Dutch-speaking learners Consequences for didactics
 The present study investigates some aspects of the learning process as an two groups multilingual learners. In particular, through examination learners’ cross-linguistic transfer occurrences we reflect on didactic consequences working with mastering several L2s. results suggest that can be influenced an...

The usual source of crosshnguistic influence in the interlanguage of a person learning a first foreign language (L2) is quite obviously his/her LI Pinpointing the source of crosshnguistic influences in the interlanguage of a multilingual speaker is less straightforward The main source of crosshnguistic influence m the L3 of a speaker is not automatically, as the present study shows, the LI of t...

BACKGROUND AND OBJECTIVES An imaginary line connecting both iliac crests is used to determine the vertebral level for lumbar puncture. This line crosses the spine at the level of L4 or the L4-L5 space. This anatomical reference can be inaccurate in a large proportion of patients. The objective of the present study was to determine whether the identification of the L3-L4 space by the physical ex...

Regulation of adenovirus major late transcription unit (MLTU) mRNA biosynthesis involves poly(A) site selection between five available sites, L1 through L5. The 5' proximal site completely dominates during early infection, whereas all five sites are used during late infection with L3 being favored slightly over the others. Previous studies have shown this early to late poly(A) switch will occur...

The effect of skeletal muscle mass (SMM) on the outcomes of sorafenib treatment for hepatocellular carcinoma (HCC) has not been established. We measured the SMM in HCC patients treated with sorafenib, evaluated the patients' survival, and evaluated the association between skeletal muscle depletion and sorafenib treatment. Of the 97 HCC patients treated with sorafenib at our institution in the p...