Basal-supported oral therapy (BOT) is often used to treat poorly controlled type 2 diabetes. However, patients sometimes experience nocturnal and early morning hypoglycemia. Thus, maintaining targeted glycemic control by BOT is limited in some patients. We assessed the efficacy and safety of replacing basal insulin by sitagliptin therapy in Japanese type 2 diabetes patients on BOT. Forty-nine s...

Background: Botulinum toxin type A (BoT-A) has gained significant clinical interest in the management of masticatory muscle pain in temporomandibular disorders (TMD). This may be due to clinical success of BoT-an in treatment of other neuromuscular and refractory chronic pain disorders in the head and neck region, and the limited understanding of the underlying pathophysiology of masticatory mu...

Abstract. We describe problems inherent in the current use of antivirus software. We note that by applying a series of program transformations, virus writers can effectively evade known signature systems. By automating this process, malware authors can keep ahead of signature-based AV systems. By using so-called “queen-bot” programs, a single bot can be kept within a perpetual zero-day window.

BACKGROUND We sought to determine the ability of the endoscopic Mueller maneuver (MM) to predict the severity of OSAS based on upper airway (UA) collapse. METHODS This chart review retrospectively analyzed the results of endoscopic Mueller maneuvers examining the UA on 506 patients suspected of having OSAS. There were 3 areas of UA collapse that were evaluated: velopharynx (VP), base of tongu...

BACKGROUND The overall prognosis of stage I borderline ovarian tumors (BOT) is excellent but a small percentage of patients die to their disease. The prognostic factors for such a rare event are still not clearly defined. The aim of this study was to determine these factors for recurrence per se and recurrence in the form of invasive carcinoma in a large series of stage I tumors. METHODS A re...

6. FERNALD, M. L. Gray's Manual of Botany. 8th ed. P. 1473. American Book Co., New York. 1950. 7. GALSTON, A. W. The effect of 2,3,5-triiodobenzoic acid on the growth and flowering of soybeans. Amer. Jour. Bot. 34: 356-360. 1947. 8. HAMNER, K. C. and BONNER, J. Photoperiodism in lelation to hormones as factors in floral initiation and development. Bot. Gaz. 100: 388-431. 1938. 9. HEMBERG, T. St...

W publikacji omówiono możliwości ChatuGPT, który jest narzędziem opartym na systemie sztucznej inteligencji przeznaczonym do generowania tekstów, tłumaczeń, analizy języka naturalnego i innych zadań związanych z przetwarzaniem naturalnego. artykule pojawia się pytanie, czy ChatGPT może w najbliższej przyszłości zastąpić nauczycieli polskiego. Choć być pomocnym dla nauczycieli, nie ich nauczaniu...

the build-operate-transfer (bot) projects are a popular method of privatization of public infrastructure development. there are several risks which might affect a bot project negatively. concession period is one of the most important decision variables in arranging a bot-type contract which should be determined considering the existing risks and uncertainties. a longer concession period is more...