نتایج جستجو برای: ژن fgf1
تعداد نتایج: 16085 فیلتر نتایج به سال:
Breast cancer is a widespread and complex disease characterized by abnormal signaling pathways that promote tumor growth progression. Despite significant medical advances the development of increasingly effective therapies for breast cancer, drug resistance reduced sensitivity to prior remain persistent challenges. Dysregulation factors such as FGFs EGF their receptors contributing factor respo...
A genome-wide phenotype screen was used to identify factors and pathways that induce proliferation of human umbilical vein endothelial cells (HUVEC). HUVEC proliferation is a recognized marker for factors that modulate vascularization. Screening "hits" included known proangiogenic factors, such as VEGF, FGF1, and FGF2 and additional factors for which a direct association with angiogenesis was n...
Heparan sulfate (HS) interacts with diverse growth factors, including Wnt, Hh, BMP, VEGF, EGF, and FGF family members, and is a necessary component for their signaling. These proteins regulate multiple cellular processes that are critical during development. However, a major question is whether developmental changes occur in HS that regulate the activity of these factors. Using a ligand and car...
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