There are hundreds if not thousands topical skin rejuvenation treatments on the market, from wrinkle creams to eye serums to lifting gels. If all of them worked as advertised, anyone with a bit of extra cash could have a skin of a fifteen year old. In reality, relatively few topical agents are clinically proven to improve wrinkles and other signs of skin aging. Others are supported by some posi...

BACKGROUND Facial massage is an extremely popular form of beauty treatment and is thought to rejuvenate the skin. We decided to study the benefits and untoward effects of this form of facial beauty treatment. METHODS One hundred and forty-two women (aged 17-63 years), who had received facial beauty treatment in three well-established beauty parlours in New Delhi, were entered into the study a...

Various claims have been made about the benefits of transdermal progesterone creams for relieving symptoms of menopause. Peer-reviewed articles have reported that the creams can raise plasma progesterone levels slightly, but have no effect on vasomotor, psychosexual or mood symptoms, bone metabolism or plasma lipid levels. Currently available progesterone creams can not be recommended for treat...

Hyperpigmentation affects people globally with negative psychological impacts. Piper betle L. leaf (PBL) extract has many benefits including skin lightening which may reduce hyperpigmentation. The objective of this study was to develop an effective skin-lightening cream containing PBL ideal characteristics. A formulation base and prepared characterized by centrifugation, particle size zeta pote...

Objective(s):Drug delivery through the skin can transfer therapeutic levels of drugs for pharmacological effects. Analgesics such as NSAIDs have gastrointestinal side effects and topical dosage forms of these drugs are mainly preferred, especially for local pains. Meloxicam is one of NSAIDs with no topical form in the market. In this research, we attempted to quantify the skin permeation of a m...

LEARNING OBJECTIVES The reader is presumed to have knowledge of the basic concepts of skin aging. After studying this article, the participant should be able to: Physicians may earn 1 AMA PRA Category 1 credit by successfully completing the examination based on material covered in this article. The examination begins on page 413. ASAPS members can also complete this CME examination online by lo...

Patient repositioning when the skin is moist, e.g., due to sweat or urine may cause skin breakdown since wetness increases the skin-support coefficient of friction (COF) and hence also the shear stresses that are generated in the skin when the patient is being moved. This everyday hospital scenario was never studied systematically however. The aim of this study was to simulate such interactions...

Patients with atopic skin show a defective barrier function both in rough and in clinically normal skin, with an increasing risk of developing contact dermatitis. Moisturizing creams are often used in the treatment of dry skin. The purpose of this study was to investigate the influence of treatment with a urea-containing moisturizer on the barrier properties of atopic skin. Fifteen patients wit...

Estimation of permeation of compounds such as chemical warfare agents (CWAs) alone or through barrier creams such as SERPACWA (Skin Exposure Reduction Paste Against Chemical Warfare Agents) requires animal experiments or in vitro testing using animal or human skin. While animal skin does not reflect the same barrier properties as human skin, human skin poses problems of procurement, cost and la...