Plants have been used as folkloric sources of medicinal agents since the beginning of mankind. As the age of modern medicine, single pure drugs emerged, and plant-derived active principles, their semi-synthetic and synthetic analogs have served as a major route to new pharmaceuticals. Since 1961, plant-derived compounds have been approved for use as anticancer drugs: vinblastine (Velban®), vinc...

Methanol, acetone and ethyl acetate extracts obtained from Verbascum pinnatifidum Vahl. V. antinori Boiss. et Heldr were investigated for their bioactive composition, antimicrobial antibiofilm activity. Antimicrobial activity was determined with Escherichia coli NRRL B-3704, Pseudomonas aeruginosa ATCC 27853, Proteus vulgaris 13315, Acinetobacter baumanii 19606), Bacillus subtilis 6633, Staphyl...

Background & Aim: Verbascum songaricum is a perennial herbaceous belongs to the Scrophulariaceae (snapdragon) family. Current study was done to study the environmental conditions effect on phytochemical properties of Verbascum songaricum leaves for extracting the effective materials. Experimental: This study was conducted at five range sites, including Hoze valley, Ghahiz, So...

The multiresistance of bacteria to antibiotics, as well as the lack of new antibiotics on the market encouraged the reasearch of antibacterial activity of non-antibiotic substances including plant extracts. During the previous decades, it has been proven that extracts of certain plants have a strong antibacterial activity, but their clinical use was limited due to the presence of organic solven...