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Antiangiogenic strategies can be effective for cancer therapy, but like all therapies resistance poses a major clinical challenge. Hypoxia and nutrient starvation select for aggressive qualities thatmay render tumors resistant to antiangiogenic attack. Here, we show that hypoxia and nutrient starvation cooperate to drive tumor aggressiveness through epigenetic regulation of the histone demethyl...
Fibrin Lysis by Thrombin Elevating Levels of Fibrinogen and Fibrin-Related Antigen (FR-Antigen) in Human Serm as Shown by AutoAnalyzer Assay' CLARENCE MERSKEY, ALAN J. JOHNSON, AND PARVIZ LALEZARI (Department of Medicine and Unit for Research in Aging, Albert Einstein College of Medice of Yeshiva University, New York, the Department of Medicine, New York Medical Center, and the Montefiore Hospi...
Evaluation of Musculoskeletal Disorders and Traumatic Injuries Among Employees at a Poultry Processing Plant Kristin Musolin Jessica G. Ramsey James T. Wassell David L. Hard Charles Mueller The Health Hazard Evaluation Program received a request from a poultry processing plant. In response to this request, NIOSH investigators evaluated ergonomic hazards, nerve damage in employees’ hands and wri...
BACKGROUND Diarrhoea is a leading cause of death and illness globally among children younger than 5 years. Mortality and short-term morbidity cause substantial burden of disease but probably underestimate the true effect of diarrhoea on population health. This underestimation is because diarrhoeal diseases can negatively affect early childhood growth, probably through enteric dysfunction and im...
6 Gastroenterology & Hepatology Volume 6, Issue 7, Supplement 10 July 2010 18 years of age and for travelers’ diarrhea caused by noninvasive strains of Escherichia coli in patients older than 12 years of age. Ongoing studies are currently investigating rifaximin in IBS. A recent phase IIb multicenter clinical trial found that rifaximin effectively provided relief of global IBS symptoms such as ...
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