نتایج جستجو برای: 063 and 004
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Over-expression of endosialin/CD248 (herein referred to as CD248) has been associated with increased tumor microvasculature in various tissue origins which makes it an attractive anti-angiogenic target. In an effort to target CD248, we have generated a human CD248 knock-in mouse line and MORAb-004, the humanized version of the mouse anti-human CD248 antibody Fb5. Here, we report that MORAb-004 ...
Carotid intima-media thickness (C-IMT) measurements provide a non-invasive assessment of subclinical atherosclerosis. The aim of the study was to assess the inter- and intra-observer variability of automated C-IMT measurements undertaken by two novice operators using the Panasonic CardioHealth Station. Participants were free from cardio-metabolic disease, and each underwent serial bilateral C-I...
BACKGROUND Lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH) mainly depend on alpha1-adrenoreceptors (α1-ADR) stimulation, but a link with oxidative stress (OS) is also involved. D-004, a lipid extract of Roystonea regia fruits, antagonizes ADR-induced responses and produces antioxidant effects. The objective of this study was to investigate whether D-004 p...
Single crystals of 70S ribosomes from Thermus thermophdus and from the wild-type and a mutant of Bacdlus stearothermophdm have been obtained. Using synchrotron X-ray beam, these crystals diffract to 19 ,~ and 35 A, respectively, and can be ~rradlated at temperatures of 110-120 K for days without noticeable decay Diffraction data sets to 22 ,~ and to 33 A with reasonable R scale v, ere collected...
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