Two cDNA species, aggst1-5 and aggst1-6, comprising the entire coding region of two distinct glutathione S-transferases (GSTs) have been isolated from a 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT) resistant strain (ZANDS) of Anopheles gambiae. The nucleotide sequences of these cDNA species share 80.2% identity and their derived amino acid sequences are 82.3% similar. They have been cla...

The 1,2,3-triazole is a well-known biologically active pharmacophore constructed by the copper-catalyzed azide–alkyne cycloaddition. We herein reported synthesis of 4-amino-7-chloro-based [1,2,3]-triazole hybrids via Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition 4-azido-7-chloroquinoline with an alkyne derivative acetaminophen. compound was fully characterized Fourier-transform infrared (FT...

In the title compound, C(17)H(13)Cl(2)N(3), the dihedral angle between the pyrazole ring system and 4-chloro-phenyl ring is 26.1 (2)°. The C=N bond linking the two aromatic rings has an E conformation.