A phytochemical investigation on the roots of Dracaena marginata yielded nine steroidal saponins. Six of the saponins were isolated as three pairs of 22-hydroxy furostanol saponins and their 22-methoxy derivatives including two new minors identified as 26-O-β-D-glucopyranosyl-22α-hydroxy-(25R)-furost-5en-3β, 26diol -3O-αLrhamnopyranosyl-(1→3)-[α-L-rhamnopyranosyl -(1→4)]–β–D -glucopyranoside an...

Background Indian traditional system of medicine uses Pithecellobium dulce for the treatment of diabetes mellitus. Objectives This study aims to develop an extract rich in saponins derived from seeds of the plant and to evaluate its antihyperglycemic potential in vitro and in vivo. Materials and Methods Defatted seeds were extracted with methanol and processed to afford saponin-enriched fra...

Saponins, a group of glycosidic compounds present in several plant species, have aglycone moieties that are formed using triterpenoid or steroidal skeletons. In spite of their importance as antimicrobial compounds and their possible benefits for human health, knowledge of the genetic control of saponin biosynthesis is still poorly understood. In the Medicago genus, the hemolytic activity of sap...

The aim of this study was to determine and compare the preventive effect of Korean White Ginseng and Red Ginseng on oxidative stress in H2O2-treated HepG2 cells. The roots of ginseng were extracted with 70% methanol and partitioned with butanol to obtain saponin fractions, which have been known as bioactive constituents of ginseng. 2',7'-Dichlorofluorescein diacetate (DCF-DA) assay and malondia...

Panax pseudo-ginseng subsp. pseudo-ginseng has a carrot like root with a small rhizome. It was shown that the saponin composition of roots and rhizomes of this subspecies collected in Tibet and China was extremely poor. From the roots and rhizomes collected in Central Nepal, (specimen-PNct), only a small amount of an oleanolic acid saponin, beta-D-glucopyranosyl-oleanolate (2) was isolated toge...

Monolayer cultures of rat hepatocytes were treated with increasing concentrations of saponin (prepared from Gypsophila plants) for 30 min at 6 degrees C. Differential permeabilization of the intracellular membranes could be demonstrated: at 0.040 mg of saponin/ml the plasma membrane was permeabilized, as assessed by the release of 50% of the total cellular amount of lactate dehydrogenase, and a...

The total saponin content, components and fatty acid composition of 14 different Tahini Halvah samples were investigated. Total saponin was determined by HPLC. The quantities of moisture, oil, protein, ash, total sugar and brix were determined with various methods. The fatty acid composition was determined by GC. Moisture, oil, protein, ash, total sugar, brix and total saponin samples from 1.22...

Extracts of the Quillaja saponaria tree contain natural surfactant molecules called saponins that very efficiently stabilize foams and emulsions. Therefore, such extracts are widely used in several technologies. In addition, saponins have demonstrated nontrivial bioactivity and are currently used as essential ingredients in vaccines, food supplements, and other health products. Previous prelimi...