This study examined the power of an exogenously generated stuttered speech signal on stuttering frequency when compared to an exogenously generated normal speech signal. In addition, we examined the speci®c components of the second speech signal, which might be responsible for the inducement of ̄uency in people who stutter. Eight males and two females who stuttered participated in this study. E...

We studied the dynamics of the process through which subjects build a visuomotor representation in memory as they learn a morphokinetic movement sequence presented on videotape. It was hypothesized that recall accuracy is closely tied to the dynamics of the movement-representation process. When analyzed in the form of time series, recall performance should exhibit a deterministic inter-trial re...

The main targets of the insecticide imidacloprid are neuronal nicotinic acetylcholine receptors (nAChRs) within the insect brain. We tested the effects of imidacloprid on ligand-gated ion channels of cultured Kenyon cells of the honeybee, Apis mellifera. Kenyon cells build up the mushroom body neuropils, which are involved in higher order neuronal processes such as olfactory learning. We measur...

The present study aimed at investigating how a specific instruction concerning gaze orientation, which involved active head motion, could influence the performance of human subjects in a self-controlled whole-body rotation task in the dark. Subjects were seated on a mobile robotic chair that they controlled using a joystick. They were asked to perform 3608 rotations while maintaining, when poss...

Calsenilin is a recently-identi®ed member of the neuronal calcium sensor family. Like other members of this family, it is found in the brain and binds calcium. Calsenilin was discovered by virtue of its interaction with both presenilin-1 and -2, proteins that are involved in the etiology of Alzheimer's disease. Because calsenilin may play a role in Alzheimer's disease and other disease with alt...

To elucidate the neural substrates of the receptive aspect of music, we measured regional cerebral blood ̄ow (rCBF) with positron emission tomography (PET) and simultaneously recorded the electroencephalogram (EEG) in eight normal volunteers. Compared with the rest condition, listening to music caused a signi®cant increase in EEG beta power spectrum (13±30 Hz) averaged over the posterior two th...

By analyzing event-related changes in induced band power in narrow frequency bands of the human electroencephalograph, the present paper explores a possible functional role of the alpha and theta rhythms during the processing of words and of sentences. The results show a phasic power increase in the theta frequency range, together with a phasic power decrease in the alpha frequency range, follo...

The NADPH-diaphorase (NADPH-d) histochemical technique is commonly used to localize the nitric oxide (NO)-producing enzyme NO synthase (NOS) in neural tissues. In the olfactory tissues of vertebrates, however, NADPH-d staining can be present without the detection of NOS by other methods. We used pharmacological controls to determine whether NADPH-d staining was indicative of NOS in olfactory ti...

Substantial evidence suggests that the accumulation of b-amyloid (Ab)-derived peptides contributes to the aetiology of Alzheimer’s disease (AD) by stimulating formation of free radicals. Thus, the antioxidant a-lipoate, which is able to cross the blood–brain barrier, would seem an ideal substance in the treatment of AD. We have investigated the potential effectiveness of a-lipoic acid (LA) agai...

Judgement of the emotional tone of a spoken utterance is influenced by a simultaneously presented face expression. The time course of this integration was investigated by measuring the mismatch negativity (MMN). In one condition, the standard stimulus was an angry voice fragment combined with a (congruous) angry face expression. In the deviant pair, the voice expression was kept the same and on...