Pedin, a peptide of 13 amino acids, stimulates foot formation in hydra, one of the simplest metazoan animals. Here, we show that the corresponding transcripts are 3.8 kb in size encoding a precursor protein with a size of about 110 kDa, which contains 13 copies of the peptide. Interestingly, the deduced amino acid sequence of the precursor comprises 27 copies of a beta-thymosin-like repeat doma...

Background and objectives: Plant extracts and their constituents are known to exert biological effects, especially antioxidant activity. Fumaria vaillantii (Fumariaceae) has several therapeutic effects in traditional medicine. Antioxidants are able to protect the human body from oxidative damage connected to the reaction of free radicals. Synthetic antioxidants have to...

1 Principal Investigator of Horticulture and Curator, USDA Naitonal Clonal Germplasm Repository for Asimina species, Atwood Research Facility, Kentucky State University, Frankfort, KY 40601-2355. To whom reprint requests should be addressed. 2 Co-Investigator of Horticulture, Atwood Research Facility, Kentucky State University, Frankfort, KY 40601-2355 Abstract The pawpaw [Asimina triloba (L.) ...

OBJECTIVE In colorectal carcinomas, tumor budding has been defined as the presence of isolated single tumor cells or small cell clusters in the stroma at the invasive tumor margin. In this study, the relationship between tumor budding density at the invasive tumor margin and pathological parameters is investigated. MATERIAL AND METHOD Haematoxylin and eosin stained slides of 73 cases with col...

BACKGROUND Our study aimed to assess the prognostic value of poorly differentiated clusters (PDCs) in invasive breast cancer. METHODS A total of 146 cases of operable invasive ductal carcinoma that was not otherwise specified (IDC-NOS), from 2002 to 2009, were pathologically reviewed. Cancer clusters with five or more cancer cells and lacking gland-like structures were counted from a field co...

To maintain genome stability during fluctuating environmental conditions, cells have adapted mechanisms to regulate cell cycle events. For unicellular organisms, such as budding yeast, this response is essential for the survival of the organism. For example, under conditions of nutrient limitation, diploid budding yeast cells enter meiosis and package the meiotic products into spores. The spore...

Previous work showed that the GTP-binding protein Rho1p is required in the yeast, Saccharomyces cerevisiae, for activation of protein kinase C (Pkc1p) and for activity and regulation of beta(1-->3)glucan synthase. Here we demonstrate a hitherto unknown function of Rho1p required for cell cycle progression and cell polarization. Cells of mutant rho1(E45I) in the G1 stage of the cell cycle did no...

Sanderia malayensis is a scyphozoan species present in the Indian and Pacific Oceans, ranging from Suez Canal to Japan. Although this jellyfish commonly kept aquariums around world, there knowledge gap regarding its biology ecology, especially at polyp stage. In study, we tested asexual reproductive activity of S. three different temperatures: 10, 15 20 °C. Results showed significant increases ...