1.2 Diagnostic criteria The condition was described by Stein and Leventhal in 1935. There is a considerable controversy on the optimal criteria for PCOS. Although the NIH (National Institute of Health) criteria as hyperandrogenic anovulatory PCOS were proposed in 1992, these have now expanded to non NIH criteria including hyperandrogenic ovulatory to nonhyperandrogenic anovulatory PCOS (2). Aft...

Polycystic ovary syndrome is the most common endocrinopathy among reproductive-aged women in the United States, affecting approximately 7% of female patients. Although the pathophysiology of the syndrome is complex and there is no single defect from which it is known to result, it is hypothesized that insulin resistance is a key factor. Metabolic syndrome is twice as common in patients with pol...

background: the prevalence of metabolic syndrome (mets) in polycystic ovary syndrome (pcos) has been studied in different populations, but their results were so controversial regarding iranian women. these controversial data indicated the need for more investigation of mets characteristics in pcos patients in our population. so this study aimed to evaluate the clinical and laboratory characteri...

background:   objective: herein we evaluated the frequency and predisposing factors of sexual dysfunction in infertile pcos patients.   materials and methods: in this cross-sectional study, 130 married women with a definite diagnosis of pcos who were referred due to infertility were recruited. they were evaluated concerning their sexual function in the domains of desire, arousal, lubrication, o...

in this study 93 hirsute females (ferryman and gallway score > 8) referred to institute of endocrinology & metabolism and office were assessed. baseline testosterone (tes), dehydroepiandrosterane sulfate (dhea-so4). follicular stimulating hormone (fsh). leuteinizing hormone (lh), prolactin (prl), thyroid stimulating hormone (tsh), baseline 17 hydroxyprogesterone (17 ohp) and in some cases acth ...

conclusions high prevalence of thyroid antibodies in euthyroid patients with pcos refers to the importance of investigation for thyroid autoimmune state in those patients. objectives the aim of this study was to evaluate the prevalence and levels of thyroid antibodies in euthyroid women with pcos in syria. patients and methods this study included 56 euthyroid women with pcos and 30 healthy wome...

In addition to its effects on reproductive health, it is now well recognized that polycystic ovary syndrome (PCOS) is a metabolic disorder, characterized by decreased insulin sensitivity which leads to an excess lifetime risk of type 2 diabetes and cardiovascular disease. PCOS patients are often obese, hypertensive, dyslipidemic and insulin resistant; they have obstructive sleep apnea and have ...

Women with polycystic ovarian syndrome have chronic anovulation and androgen excess not attributable to another cause. This condition occurs in approximately 4% of women. The fundamental pathophysiologic defect is unknown, but important characteristics include insulin resistance, hyperandrogenism, and altered gonadotropin dynamics. Inadequate follicle-stimulating hormone is hypothesized to be a...

PCOS is characterised by a varied and often complex array of metabolic and endocrine abnormalities. The syndrome was originally described by Stein and Leventhal in 1935, as a triad consisting of amennorhoea, hirsutism and obesity, in women who had multiple cysts on their ovaries.1 Over the last decade or so, the understanding of this syndrome has changed and the emphasis is often on the long-te...

Objective: To study the effects of exenatide combined with clomifene citrate on the levels of Angiotensin (Ang) II/Angiotensin-(1-7) and insulin resistance in patients with polycystic ovary syndrome (PCOS). Methods: A total of 78 patients with PCOS who were treated in our department from January 2015 to January 2017 were included in the study. Patients were randomly divided into observation gro...