نتایج جستجو برای: 171
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Abstract Background The profound changes wrought by COVID-19 on routine hospital operations may have influenced performance measures, including healthcare-associated infections (HAIs). Objective Evaluate the association between surges and HAI or cluster rates Methods Design: Prospective cohort study Setting 148 HCA Healthcare-affiliated hospitals, 3/1/2020-9/30/2020, a subset of hospitals with ...
The ubiquitin-proteasome pathway regulates bone formation through osteoblast differentiation. We analyzed variation alkaline phosphatase (ALP) during carfilzomib treatment. Data from 38 patients enrolled in the PX-171-003 and 29 patients in PX-171-004 studies, for patients with relapsed/refractory myeloma, were analyzed. All patients received 20 mg/m(2) of carfilzomib on Days 1, 2, 8, 9, 15, an...
Dans l’administration, les carrières des femmes progressent sous le plafond de verre. Au-delà chiffres, l’analyse trajectoires fonctionnaires du ministère la Culture révèle dynamique organisationnelle ces inégalités. Fondée sur récits vie 65 membres l’encadrement supérieur (administration centrale et Drac), cette étud...
The objective of this study was to develop a reliable Taqman 5' Nuclease Assay for genotyping sheep for scrapie susceptibility. The sheep prion gene contains 2 single nucleotide polymorphisms (SNPs) that may mediate resistance to classical scrapie, one at codon 136, alanine (A) or valine (V), and another at codon 171, arginine (R) or glutamine (Q). The R allele appears to confer resistance to c...
In eukaryotic species from yeast to human, stress-activated protein kinases (SAPKs), members of a MAP kinase (MAPK) subfamily, regulate the transcriptional response to various environmental stress. It is poorly understood how diverse forms of stress are sensed and transmitted to SAPKs. Here, we report the heat shock regulation of the fission yeast Spc1 SAPK, a homolog of human p38 and budding y...
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