In this work, a new cadmium(II) complex namely the (1,4-diazabicyclo[2.2.2]octane)(meso-tetrakis(4-tert-methoxyphenyl)porphyrinato)cadmium(II) with formula [Cd(TMPP)(DABCO)] (I) (DABCO = 1,4-diazabicyclo[2.2.2]octane) was successfully synthetized. The structure of have been characterized by FT-IR, 1HNMR, UV–visible, fluorescence spectroscopies and single crystal X-ray diffraction technique. DFT...

Antimicrobial textiles have played an increasingly important protection role in the medical field. With this aim, Schiff bases and nanometal complexes on cotton fabric were situ synthesized for achieving conventional fabric’s highly efficient durable UV antibacterial properties. Herein, a new base derived from condensation reaction of 2,4-dihyroxybenzaldehyde with p-amino aniline was synthesize...

Suzuki cross coupling reaction is one of the most famous organic reactions 20th century’s chemistry. It deemed as in field a very effective method for making carbon–carbon bonds. has been extensively utilized synthesis many carbon molecules including complex ones.Syntheses 2-diethylamino-4H-7-(Het) aryl pyrido [1,2-a] [1,3,5] triazin-4-ones are currently under investigation order to obtain grea...

Our recent work displays the successful preparation of Schiff_bases that carried out between hexane-2,5-dione and 2 moles (Z)-3-hydrazineylideneindolin-2-one forming in Schiff-bases-(L), Which turn allowed combining with each next metal ions: (M2+) = Ni, Mn, Zn, Cu Co complexes_ high stability. The formation resulting Schiff_ bases (L) is detected spectrally using LC_Mss which gave approximatel...

A new series of N-Mannich bases 2-Phenyl-5-benzimidazole sulfonic acid have been synthesized through amino methylation reaction with secondary amines. The two moieties were held together a methylene bridge, which comes from formaldehyde (Formalin Solution 37%) used in the reaction. Chemical structures newly compounds confirmed using FT-IR, 1HNMR and 13CNMR. Different vitro assays including Anti...

The present work describesthe development of highly potent mushroom tyrosinase inhibitor better than the standard kojic acid. Carvacrol derivatives 4a-f and 6a-d having substituted benzoic acid and cinnamic acidresidues were synthesized with the aim to possess potent tyrosinase inhibitory activity.The structures of the synthesized compounds were ascertained by their spectroscopic data (FTIR, 1H...

As chitosan’s solubility represents a drawback for further applications, the functionalization of chitosan became attractive by a variety of chemical methods. The present study deals with the chemical modification of chitosan by using click chemistry technique as versatile tool being easy to perform with high yields and no additional by products. The approach used herein was to attach a respons...

Purpose: To study the enzyme inhibition activity of various sulfonamides derived from dagenan chloride. Methods: The synthesis of N-(naphthalen-1-yl)-4-acetamidobenzenesulfonamide (3) was carried out by gearing up 1-naphthylamine (1) with dagenan chloride (2) in water in the presence of Na2CO3 solution. Further, compound 3 was treated with various alkyl/aralkyl halides (4a-o) to yield 5a-o in a...

Dihydrofolate reductase (DHFR) is an important enzyme for de novo synthesis of nucleotides in Plasmodium falciparum and it is essential for cell proliferation. DHFR is a well known antimalarial target for drugs like cycloguanil and pyrimethamine which target its inhibition for their pharmacological actions. However, the clinical efficacies of these antimalarial drugs have been compromising due ...