This paper presents a hybrid algorithm that prioritizes the suppliers and then allocates the demand among the suppliers. The objective here is to maximize the total purchase value of the items taking into consideration budget constraint, demand condition, delivery lead-time and supplier capacity. Since the problem is multi-criteria decision making, we solve this problem by integrating the suppl...

Some methods from statistical machine learning and from robust statistics have two drawbacks. Firstly, they are computer-intensive such that they can hardly be used for massive data sets, say with millions of data points. Secondly, robust and non-parametric confidence intervals for the predictions according to the fitted models are often unknown. Here, we propose a simple but general method to ...

Peers are used to limit and expand the available facilities for different kind of devices, which should able to fetch the data according to the demand of users and available resources. Several factors such as latency, bandwidth, memory size, CPU speed, and reliability can affect the Quality of Service (QoS) of the peer-to-peer network. In this paper, we propose a signaling system for QoS-aware ...

BACKGROUND Neonatal pain management has received increasing attention over the past four decades. Research into the effects of neonatal pain emphasises the professional, ethical and moral obligations of staff to manage pain for positive patient outcomes. However, evaluation studies continuously report evidence of inadequate neonate pain management and a gap between theory and practice. OBJECT...

In this paper we present some results obtained when comparing classic Genetic Programming (GP) with the isolated multipopulation version. Our first discovery was that sometimes, given a certain number of individuals, it is useful to distribute them among several populations even when no communication is allowed. 1 ISOLATED MULTIPOPULATIONS GENETIC PROGRAMMING Using a large population is not alw...

Neutralact(R), the DSM brand name of a lactase enzyme preparation, obtained from a homologous rDNA strain of Kluyveromyces lactis, was subjected to a series of toxicological tests to document the safety for use as a processing aid in the dairy industry. The enzyme preparation was examined for subacute oral toxicity and mutagenic potential. As a result of these tests, no evidence of oral toxicit...

OBJECTIVES This study aimed to explore the period between onset of pain and hospital-admission (pain-to-admission time) in patients with acute pancreatitis (AP), to investigate the prognostic value and associated factors of this time, and to ascertain the knowledge about the pancreas in these patients. METHODS An analysis of a prospective multicenter study was done, which included 188 patient...

OBJECTIVE To establish normative adductor squeeze test (AST) values in elite junior rugby union players and investigate if differences existed between field position units and categorizations. DESIGN Cross-sectional study. SETTING National underage screening camp. PARTICIPANTS One hundred four healthy players attending an under-19 and under-18 national musculoskeletal and fitness screenin...

This paper discusses two classes of distributions, and stochastic processes derived from them: modified stable (MS) laws and normal modified stable (NMS) laws. This extends corresponding results for the generalised inverse Gaussian (GIG) and generalised hyperbolic (GH) or normal generalised inverse Gaussian (NGIG) laws. The wider framework thus established provides, in particular, for added fle...