According to the principles of the methodology of bioisosteric replacements a series of methyl 1-R-4-methyl-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxylates has been obtained as potential analgesics. In addition, a fundamentally new strategy for the synthesis of compounds of this chemical class involving the introduction of N-alkyl substituent at the final stage in 2,1-benzothiazine nucleus alre...

In the title compound, [Y(C(5)H(2)N(2)O(4))(C(5)H(3)N(2)O(4))(C(12)H(8)N(2))(2)]·2H(2)O, the Y(III) ion lies on a twofold rotation axis and exhibits a distorted square-anti-prismatic coordination geometry. It is chelated by two 1,10-phenanthroline ligands, a 2,4-dioxo-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate mono-anion and a 4-oxido-2-oxo-1,2-dihydro-pyrimidine-5-carboxyl-ate dianion. The ...

The high valent molybdenum-dioxo complex [MoO2Cl2] catalyzes the addition of dimethylphenylsilane to aldehydes and ketones to afford the corresponding dimethylphenylsilyl ethers in quantitative yield.

In this work, the effect of functional groups on I 2 sorption kinetics is investigated using two different types isostructural metal‐organic frameworks, UiO‐66‐X series (X = H, Br, NO , NH (OH) and (COOH) ) M ( m ‐DOBDC) series, (M Co2+, Mg2+, Ni2+; ‐DOBDC 4− 4,6‐dioxo‐1,3‐benzenedicarboxylate). Among UiO‐66‐(COOH) exhibits fastest highest capacity due to dipole‐induced dipole interactions betw...

A series of novel 2, 4-thiazolidinedione derivatives 2-{4-[(E)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl] phenoxy}N-(substituted phenyl) acetamides d (1-12) have been accomplished in good yields by stirring 2,4-thiazolidinedione a and 2-(4-formyl phenoxy) N-substituted acetamide c (1-12) at room temperature. Some of the reaction sequences were carried under microwave irradiation which resulte...

IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: bis-(tri-ethyl-ammonium) 2,5-di-chloro-3,6-dioxo-cyclo-hexa-1,4-diene-1,4-diolate], 2C6H16N(+)·C6Cl2O4 (2-), the chloranilate anion lies on an inversion center. The tri-ethyl-ammonium cations are linked on both sides of the anion via bifurcated N-H⋯(O,O) and weak C-H⋯O hydrogen bonds to give a centrosymmetric 2:1 aggregate. The 2:...