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BACKGROUND The objective of this phase I study was to determine the maximum tolerated dose (MTD) and recommended dose (RD) of preoperative chemoradiotherapy (CRT) with S-1 plus oxaliplatin in patients with locally advanced rectal cancer. METHODS Patients received radiotherapy in a total dose of 50.4 Gy in 28 fractions. Concurrent chemotherapy consisted of a fixed oral dose of S-1 (80 mg/m(2)/...
in order to evaluate the possible immunosuppressive effects of coccidial infection on cell mediated immunity (cmi) of broiler chickens, 640 ross male day old broiler chicks were randomly divided into 4 equal groups of 160 (each consist of 4 replicates of 40). the negative control group remained unchallenged, while the other three groups challenged with 3 different levels of high, medium and low...
OBJECTIVE To reassess endometrial morphological criteria of normality identifying the best morphological and molecular "implantation window" indicators in normal women. DESIGN Prospective clinical study. SETTING Assisted reproductive unit. PATIENT(S) Fourteen healthy volunteers. INTERVENTION(S) Blood sampling for LH, E(2), and progesterone (P4) determinations. Daily vaginal ultrasounds....
The relationship between plasma molybdenum (Mo) and dietary intake has not been investigated in humans. We developed an isotope dilution method to determine molybdenum in 0.5 mL blood plasma by ICP-MS and conducted a study to determine the effect of dietary intake on plasma molybdenum. Twelve young men consumed a very low Mo diet (22 microg/day) for 24 days while confined to the WHNRC metabolic...
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