Abstract Introduction Stress is associated with erectile dysfunction (ED), however, it not clear whether psychological stressors affect the vasculature and tissue in a manner that could contribute to vasculogenic dysfunction. A positive correlation between hyperprolactinemia, stress has been demonstrated, interestingly, prolactin was shown decrease endothelium nitric oxide endothelium- dependen...

To determine the if Vitamin D3 supplementation reduces incidence of gestational diabetes (GDM). : A subgroup analysis efficacy to prevent GDM was completed on a trial performed from 10/2016 - 4/2020. Women with confirmed intrauterine pregnancy 12-16 weeks gestation were included. taking supplements, or malabsorption disorder, carrying anomalous fetus had mellitus excluded. assigned receive dail...

It is important to treat patients with Cushing's disease as rapidly as possible to limit its long-term mortality and morbidity. Selective transphenoidal pituitary adenomectomy remains the treatment of choice but, unfortunately, the rate of cure at long-term follow-up is suboptimal and recurrences are high, even in the hands of expert neurosurgeons. Treatment options for persistent or relapsed d...

Four ADR1c mutations that occur close to Ser-230 of the Saccharomyces cerevisiae transcriptional activator ADR1 and which greatly enhance the ability of ADR1 to activate ADH2 expression under glucose-repressed conditions have been shown to reduce or eliminate cyclic AMP-dependent protein kinase (cAPK) phosphorylation of Ser-230 in vitro. In addition, unregulated cAPK expression in vivo blocks A...

One hundred eighty-eight male calves were randomly assigned to one of five treatments at about 6 wk of age t o determine the effect of castration at different weights on feedlot performance and carcass characteristics. Calves were castrated at 70, 230. 320 or 410 kg or left intact. All calves received a 36-mg zeranol implant 6 0 d postweaning and were re-implanted every 56 d for the duration of...

Background Giant cell arteritis (GCA) is the most common form of primary systemic vasculitis in patients aged >50 years. It predominantly affects cranial arteries; however, extra-cranial disease involving aorta and its major branches can also be present. According to 2018 EULAR recommendations, ultrasound temporal arteries (TAs), with or without axillary (AXs), should first imaging modality ...

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AIM To compare the intermediate-term efficacy of a large surface area Baerveldt 350 mm2 glaucoma drainage device (GDD) with medium surface area implants (Baerveldt 250 mm2 and Molteno 3, 230, or 245 mm2). DESIGN This is a retrospective, nonrandomized comparative trial. MATERIALS AND METHODS A total of 94 eyes of 94 patients of mixed glaucoma diagnoses without any prior glaucoma surgical pro...

The strength of Atlantic meridional overturning circulation is believed to affect the climate over glacial-interglacial and millennial timescales. The marine sedimentary (231)Pa/(230)Th ratio is a promising paleocirculation proxy, but local particle effects may bias individual reconstructions. Here we present new Atlantic sedimentary (231)Pa/(230)Th data from the Holocene, the last glacial maxi...