In the alpha7 nicotinic acetylcholine receptors, we analyze the contribution of mutations E237A and V251T, together with the proline insertion P236', in the conversion of the charge selectivity from cationic to anionic. We show that the triple mutant exhibits spontaneous openings displaying anionic selectivity. Furthermore, at position 251, hydrophilic or even negatively charged residues are co...

1 Incomplete Spinal Cord Injury 2 3 4 Keith E. Gordon, Ming Wu, Jennifer H. Kahn, and Brian D. Schmit 5 Sensory Motor Performance Program, Rehabilitation Institute of Chicago 6 Department of Physical Medicine and Rehabilitation, Northwestern University Medical School 7 Department of Biomedical Engineering, Marquette University 8 9 Running Head: Locomotor Adaptation to Ankle-Foot Load 10 11 Corr...

A new, simple, fast and reliable zero order spectrophotometric method has been developed for determination of Escitalopram Oxalate in bulk and tablet dosage forms. The quantitative determination of drug was carried out using the zero order values (absorbance) measured at 238 nm. Calibration graph constructed at 238 nm was linear in concentration range of 2-20 µg/ml with correlation coefficient ...

conclusion: in this study group, tnf-α -238 polymorphism was shown to be different in preeclamptic and non-preeclamptic pregnant women. the aa genotype and the a allele may carry an increased risk for developing of preeclampsia. results: there were significant differences between the two groups in tnf-α genotype at position -238 (p < 0.001). in the preeclamptic group, the frequency of the aa ge...

OBJECTIVES TNF-alpha is a critical cytokine produced by Th1 cells while altered T helper 1 (Th1)-Th2 balance is found crucial for a successful pregnancy. STUDY DESIGN A cohort of 132 Southern Chinese Han RSA patients and 152 controls constituted the subjects of this study. Two functional polymorphisms -308 and -238 of TNF-alpha were studied by association analysis. RESULTS lack of associati...

The small anode germanium (SAGe) Well detector from Canberra Industries with a cosmic veto supression system was tested on marine particles and water samples. The cosmic-veto suppression system reduced the shielded background by an average of 35 % across the energy spectrum. The enhanced energy resolution and efficiency improved the ability to separate the major U-238 decay chain energies 92, 2...

INTRODucnON ... ......... ........... .. . .. ........ ... ........ . .. .. ... .. ... . ......... .. ........ . 238 Structure oj the Cell Envelope.................................................................. 238 Uptake Arross the Outer Membrane.......................................................... 239 Intrinsic,Dejects in Outer Membrane Permeability in So.me Bacteria . .... ..... .. ....

Covid-19 has affected the education sector in Indonesia. The purpose of this study was to determine decay rate Carbon-14 and Uranium-238 isotopes first half, second third level accuracy experiment using PhET Simulation. method used research is experimental method. results showed percentage half 49%, half-life 75.4%, 84.5%. While Uranium-238's 49.6%, 74%, 85.9%. for isotope Simulation 98.35%, wh...