Healthy subjects ingested2H2O.2H enriched the hydrogen bound to carbon 1 of blood glucose 1.3 to 1.8 times more than the hydrogens bound to carbon 6. Enrichment at carbon 1 was more than at carbon 5 after 14 h, but not after 42 h, of fasting. After overnight fasting, when [2,3-3H]succinate was infused, 34 times as much 3H was bound to carbon 6 as to carbon 1. On [1-2H,1-3H,1-14C]galactose infus...