نتایج جستجو برای: 3 thiazole
تعداد نتایج: 1812778 فیلتر نتایج به سال:
Thiazole is an important nucleus owing to its wide range of medical uses. It contains components that are anti-bacterial, anti-fungal, anti-malarial, anti-cancer, anti-allergic, anti-hypertensive, anti-inflammatory, and anti-psychotic, as well antioxidant, analgesic, antimicrobial. The thiazole scaffold has been detected in the more than eighteen FDA-accepted medicines addition countless resear...
Owing to their potent cytotoxicity against tumor cells, including taxol (paclitaxel)-resistant cell lines, the epothilones (for example, epothilone A (1) and epothilone B (2)) continue to be the focus of intense chemical, biological, and clinical research efforts around the world. 3] Following the findings that cyclopropane-, methylsulfanylthiazole-, and pyridine-containing epothilone B derivat...
Gene locus specificity of the glucose effect in the thiamine pathway of the angiosperm, Arabidopsis.
All mutants at 3 loci in Arabidopsis thaliana (L.) Heynh., a higher plant, that are associated with the synthesis or coupling of the thiazole moiety of thiamine are susceptible to reversible glucose inhibition. In contrast, several different alleles involved in the synthesis of the pyrimidine moiety of the vitamin are insensitive to glucose. Glucose and maltose are equally effective inhibitors ...
Purpose: We previously identified novel thiazole derivatives able to reduce histone acetylation and histone acetyltransferase (HAT) activity in yeast. Among these compounds, 3-methylcyclopentylidene[4-(40-chlorophenyl)thiazol-2-yl]hydrazone (CPTH6) has been selected and used throughout this study. Experimental Design: The effect of CPTH6 on histone acetylation, cell viability and differentiatio...
A Thiazole Orange conjugated with folate derivative was synthesized in two steps. Firstly, folate was coupled with 1-(3-aminopropyl)-4-methylquinolinium bromide to afford folate-methylquinolinium bromide, which then reacted with benzothiazolium to obtain the title folate-conjugated compound. The compound was evaluated by ¹H-NMR MS, TG/DTA and fluorescence spectroscopic methods. The title compou...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید