نتایج جستجو برای: 300 day

تعداد نتایج: 418963  

2015
Makoto Sato Setsuko Todoriki Tetsuyuki Takahashi Ezar Hafez Chie Takasu Hisanori Uehara Kohji Yamakage Takashi Kondo Kozo Matsumoto Masakazu Furuta Keisuke Izumi

A 90-day oral toxicity test in rats was performed to evaluate the toxicity of 2-tetradecylcyclobutanone (2-tDCB), a unique radiolytic product of stearic acid. Six-week-old male and female F344 rats (n=15/group) were given 2-tDCB at concentrations of 0, 12, 60 and 300 ppm in a powder diet for 13 weeks. Slight dose-dependent increases in serum total protein and albumin in male rats were found, bu...

Journal: :Hypertension 2014
Joanna Balcarek Bruno Sevá Pessôa Catherine Bryson Michel Azizi Joël Ménard Ingrid M Garrelds Gerard McGeehan Richard A Reeves Sue G Griffith A H Jan Danser Richard Gregg

This study compared the pharmacodynamic/pharmacokinetic profile of the new renin inhibitor VTP-27999 in salt-depleted healthy volunteers, administered once daily (75, 150, 300, and 600 mg) for 10 days, versus placebo and 300 mg aliskiren. VTP-27999 was well tolerated with no significant safety issues. It was rapidly absorbed, attaining maximum plasma concentrations at 1 to 4 hours after dosing,...

Journal: :تولیدات دامی 0
فرزانه رحیمی نیت دانشجوی کارشناسی ارشد، گروه علوم دام و طیور، پردیس ابوریحان، دانشگاه تهران شکوفه غضنفری استادیار گروه علوم دام و طیور، پردیس ابوریحان، دانشگاه تهران سید داود شریفی دانشیار گروه علوم دام و طیور، پردیس ابوریحان، دانشکاه تهران

this experiment was conducted to evaluate the effects of different levels of artemisia sieberi oil (zero, 100, 200 and 300 mg/kg) and antibiotic on performance and blood parameters in broiler chicken. 200 day-old broiler chickens (ross 308) were allocated to five treatments, four replications with a completely randomized design. in total period, broilers were fed dietary artemisia sieberi oil a...

1996
Marcia Derr Jacques Durand Michael Doherty Richard Hull Mohammed Rupawalla

There are many applications which arise in telecommunications information processing in which it is useful, and often necessary, to create and access multiple hypothetical states. These might correspond to future states reeecting pending updates (such as customer service orders), or hypothetical alternative states that would arise in the exploration of diierent solutions to a given problem. In ...

Journal: :The New England journal of medicine 2017
Aleena Banerji Paula Busse Mustafa Shennak William Lumry Mark Davis-Lorton Henry J Wedner Joshua Jacobs James Baker Jonathan A Bernstein Richard Lockey H Henry Li Timothy Craig Marco Cicardi Marc Riedl Ahmad Al-Ghazawi Carolyn Soo Ryan Iarrobino Daniel J Sexton Christopher TenHoor Jon A Kenniston Ryan Faucette J Gordon Still Harvey Kushner Robert Mensah Chris Stevens Joseph C Biedenkapp Yung Chyung Burt Adelman

BACKGROUND Hereditary angioedema with C1 inhibitor deficiency is characterized by recurrent, unpredictable swelling episodes caused by uncontrolled plasma kallikrein generation and excessive bradykinin release resulting from cleavage of high-molecular-weight kininogen. Lanadelumab (DX-2930) is a new kallikrein inhibitor with the potential for prophylactic treatment of hereditary angioedema with...

Journal: :Saudi medical journal 2004
Mohammad Z Zailaie

OBJECTIVE Recent in vitro and in vivo studies have shown that the nonsteroidal anti-inflammatory agent, acetylsalicylic acid (ASA) or aspirin has antioxidant properties on various cell lines and tissues. Hence, the aim of the present study is to investigate the effects of ASA at 2 different concentrations (75 and 300 microg/ml) on the proliferative capacities and lipid peroxidation of in vitro ...

Journal: :Epilepsia 2008
Montserrat Vera-Llonch Nancy A Brandenburg Gerry Oster

PURPOSE To estimate the cost-effectiveness of pregabalin as add-on therapy in patients with refractory partial epilepsy. METHODS We developed a model to estimate clinical and economic outcomes over 1 year in a hypothetical cohort of patients with refractory partial epilepsy assumed alternatively to receive add-on therapy with pregabalin (300 mg/day) or no add-on therapy. For each patient in t...

2003

w Liver peroxisoma115-oxidation activity on stearate, oleate, linoleate and ct-linolenate was investigated as a funtion of age in two mouse strains. Each fatty acid showed a similar I~-oxidation activity pattern with age characterized by a rapid increase (200%) from day 2 to 20 followed by a dramatic weaning-related decrease (70%) from day 20 to 22. There was a new increase (260%) from day 22 t...

2017
Karthik Rajkumar

We have seen that the BH procedure controls the FDR for multiple testing when the p-values are independent. How can we control the FDR under dependence? Here, we consider the case where the statistics have distribution Y ∼ N (μ,Σ); in the past, we have assumed that Σ = Ip. If the covariance matrix Σ were known, we could reduce to the independent case using the transformation Y ′ = Σ− 1 2Y , so ...

2015
ALAN G. ROBINSON JOSEPH G. VERBALIS

• The posterior pituitary is neural tissue and consists only of the distal axons of the hypothalamic magnocellular neurons that make up the neurohypophysis. • The control of hormone synthesis is at the level of transcription. Stimuli for secretion of vasopressin or oxytocin also stimulate transcription and increase the messenger ribonucleic acid (mRNA) content in the magnocellular neurons. • Th...

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