We have observed the dynamics of sarcomere shortening and the diffracting action of single, functionally intact, unattached cardiac muscle cells enzymatically isolated from the ventricular tissue of adult rats. Sarcomere length was measured either (a) continuously by a light diffraction method or (b) by direct inspection of the cell's striated image as recorded on videotape or by cinemicroscopy...

PURPOSE To demonstrate experimentally, by means of histological and histomorphometric examinations, the sclera and choroid degenerative alterations, which take place at an early stage due to a hypercholesterolemic diet. METHODS New Zealand rabbits were divided into two groups: CG (control group) of 6 rabbits (6 eyes) received a regular diet for 6 weeks; G1, of 12 rabbits (12 eyes), was first ...

Chloroplast DNA (ctDNA) from the marine chromophytic alga, Olisthodiscus luteus, has been isolated using a whole cell lysis method followed by CsCl-Hoechst 33258 dye gradient centrifugation. This DNA, which has a buoyant density of 1.691 grams per cubic centimeter was identified as plastidic in origin by enrichment experiments. Inclusion of the nuclease inhibitor aurintricarboxylic acid in all ...

Effects of the neutralization of endogenous progesterone with rabbit antiserum to progesterone (anti-progesterone) on germinal vesicle breakdown of ova in follicles of small (less than 125 micrometers), intermediate (125-250 micrometers) and large (greater than 250 micrometers) diameter were examined by a quantitative histological technique. Immature rats were treated with 5 IU pregnant mare's ...

We describe a novel three-dimensional fluorescence lifetime imaging microscope that exploits structured illumination to achieve whole-field sectioned fluorescence lifetime images with a spatial resolution of a few micrometers.

We report a phase diagram mapping for solid hydrogen based on several thousands of Raman spectroscopic data points obtained at simultaneous high-pressure and -temperature (PT) experiments. Information about behavior in the range 300 K up to melting line 0--300 GPa has remained almost unknown date; therefore, revealing it is very desirable. A network analysis isothermal isobaric dependencies var...

(11:21); hence from the very nature of creation Browne may conclude: "All things began in order, so shall they end, and so shall they begin again; according to the ordainer of order and mystical mathematics of the City of Heaven." Browne could not know in 1658 that he would live for another 24 years. As though The Garden of Cyrus is actually his final work he joins it, like a snake swallowing i...

We have seen that the BH procedure controls the FDR for multiple testing when the p-values are independent. How can we control the FDR under dependence? Here, we consider the case where the statistics have distribution Y ∼ N (μ,Σ); in the past, we have assumed that Σ = Ip. If the covariance matrix Σ were known, we could reduce to the independent case using the transformation Y ′ = Σ− 1 2Y , so ...

• The posterior pituitary is neural tissue and consists only of the distal axons of the hypothalamic magnocellular neurons that make up the neurohypophysis. • The control of hormone synthesis is at the level of transcription. Stimuli for secretion of vasopressin or oxytocin also stimulate transcription and increase the messenger ribonucleic acid (mRNA) content in the magnocellular neurons. • Th...