نتایج جستجو برای: 34 dihydropyrimidin 21h ones
تعداد نتایج: 236634 فیلتر نتایج به سال:
An efficient chiral squaramide-catalysed enantioselective Michael addition of pyrazolin-5-ones to nitroalkenes has been developed. This reaction afforded the chiral pyrazol-3-ol derivatives in high to excellent yields (up to >99%) with high enantioselectivities (up to 94% ee) for most substrates under very low catalyst loading (0.25 mol%). This catalytic asymmetric reaction provides valuable an...
A highly practical and efficient preparation of 3,4-Dihydropyrimidin-2(1H)-one derivatives was developed via an efficient and simple nanocatalyst and promoted multi-component reaction of ethyl acetoacetate, aromatic aldehyde, and urea in the presence of a catalytic amount of (CTA)3[SiW12]-Li+-MMT under solvent-free conditions. In comparison to the conve...
Phosphonated isoxazolinyl nucleosides have been prepared via 1,3-dipolar cycloaddition reaction of nitrile oxides with corresponding vinyl or allyl nucleobases for antiviral studies. The cytotoxicity, the anti-HSV activity and the RT-inhibitory activity of the obtained compounds were evaluated and compared with those of AZT and diethyl{(1'SR,4'RS)-1'-[[(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1...
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