Tavares, Wendy, Daniel J. Drucker, and Patricia L. Brubaker. Enzymaticand renal-dependent catabolism of the intestinotropic hormone glucagon-like peptide-2 in rats. Am. J. Physiol. Endocrinol. Metab. 278: E134–E139, 2000.— The intestinotropic hormone glucagon-like peptide (GLP)-2(1—33) is cleaved in vitro to GLP-2-(3—33) by dipeptidyl peptidase IV (DP IV). To determine the importance of DP IV v...

Zhang, Junlong, and Christopher D. Byrne Differential hepatic lobar gene expression in offspring exposed to altered maternal dietary protein intake. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G128–G136, 2000.—Increased plasma fibrinogen concentrations are a recognized risk factor for coronary heart disease, and increased fibrinogen levels in adults are associated with parameters of reduc...

Elliott, Susan N., J. L. Wallace, W. McKnight, D. G. Gall, J. A. Hardin, M. Olson, and A. Buret. Bacterial colonization and healing of gastric ulcers: the effects of epidermal growth factor. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G105–G112, 2000.—Experimental gastric ulcers are rapidly colonized by various bacteria, resulting in significantly impaired healing. Epidermal growth factor...

PAULINE B. DARLING,1,2 JOHN GRUNOW,1,3 MAHROUKH RAFII,1 STEVE BROOKES,4 RONALD O. BALL,2,5 AND PAUL B. PENCHARZ1–3,5 1The Research Institute, Hospital for Sick Children, Toronto, Ontario M5G 1X8; Departments of 2Nutritional Sciences and 3Pediatrics, University of Toronto, Ontario M5S 3E2; 5Department of Agricultural, Food & Nutritional Sciences, University of Alberta, Edmonton, Alberta, Canada ...

Casey, Anna, Rob Mann, Katie Banister, John Fox, Peter G. Morris, Ian A. Macdonald, and Paul L. Greenhaff. Effect of carbohydrate ingestion on glycogen resynthesis in human liver and skeletal muscle, measured by 13C MRS. Am. J. Physiol. Endocrinol. Metab. 278: E65–E75, 2000.— This study investigated the effect of carbohydrate (CHO) ingestion on postexercise glycogen resynthesis, measured simult...

Shangraw, Robert E., and Farook Jahoor. Lipolysis and lipid oxidation in cirrhosis and after liver transplantation. Am J Physiol Gastrointest Liver Physiol 278: G967– G973, 2000.—On the basis of the finding that plasma glycerol concentration is not controlled by clearance in healthy humans, it has been proposed that elevated plasma free fatty acid (FFA) and glycerol concentrations in cirrhotic ...

Buéno, Lionel, Jean Fioramonti, and Rafael GarciaVillar. Pathobiology of Visceral Pain: Molecular Mechanisms and Therapeutic Implications. III. Visceral afferent pathways: a source of new therapeutic targets for abdominal pain. Am J Physiol Gastrointest Liver Physiol 278: G670–G676, 2000.—Visceral pain is the major cause of consulting in gastroenterology and the principal symptom of functional ...

Park, Hyung Seo, Hyeok Yil Kwon, Yun Lyul Lee, William Y. Chey, and Hyoung Jin Park. Role of GRPergic neurons in secretin-evoked exocrine secretion in isolated rat pancreas. Am J Physiol Gastrointest Liver Physiol 278: G557–G562, 2000.—Effects of intrapancreatic gastrin-releasing peptide (GRP)-containing neurons on secretin-induced pancreatic secretion were investigated in the totally isolated ...

Sonoyama, Kei, Suriya Rutatip, and Takanori Kasai. Gene expression of activin, activin receptors, and follistatin in intestinal epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G89–G97, 2000.—Gene expression of activin, activin receptors, and follistatin was investigated in vivo and in vitro using semiquantitative RT-PCR in intestinal epithelial cells. Rat jejunum and the int...

Sodeman, Thomas, Steven F. Bronk, Patricia J. Roberts, Hideyuki Miyoshi, and Gregory J. Gores. Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas. Am J Physiol Gastrointest Liver Physiol 278: G992–G999, 2000.—Toxic bile salts induce hepatocyte apoptosis by a Fas-dependent, Fas ligand-independent mechanism. To account for this observation, we formulated the hyp...