Human interleukin-2 (IL-2), OK-432 and mouse interferon-gamma (IFN-gamma) were evaluated for their beneficial effects on in vitro induction of nonspecific killer cells by concanavalin A (Con A). Nonspecific killer cells could be induced by culturing C57BL/6 spleen cells for 4 days with Con A. Con A activated killer cells showed direct cell-mediated cytotoxicity (DCMC) and lectin-dependent cell-...

A ranula is a mucus retention cyst or pseudocyst caused by leakage of mucus from the sublingual gland and generally occurs in the oral floor. In addition, drug induced hypersensitivity syndrome (DIHS) is a rare but well-recognized serious adverse effect characterized by fever, skin rashes, generalized lymphadenopathy, hepatitis, and hepatosplenomegaly and oral stomatitis. This paper presents th...

Introduction: Cystic hygroma is a type of lymphangioma and is located most frequently in the head and neck region, followed by axilla, superior mediastinum, and mesentery and retroperitoneal. Its occurrence in upper extremity is rarely reported in literature. Case Report: We report a newborn baby with Down’s syndrome presented with cystic hygroma in his left arm and forearm. Patient was treated...

The metacaspase Mca1 from Saccharomyces cerevisiae displays a Q/N-rich region at its N-terminus reminiscent of yeast prion proteins. In this study, we show that the ability of Mca1 to form insoluble aggregates is modulated by a peptide stretch preceding its putative prion-forming domain. Based on its genomic locus, three potential translational start sites of Mca1 can give rise to two slightly ...

appearance of the ‘tail sign’ is vital for distinguishing plunging ranulas. However, these images are insufficient to differentiate between cystic hygroma, second branchial cleft cyst, or dermoid cysts [4]. USG can be used preoperatively to determine the characteristics of pediatric ranulas, and are a radiation-free and a rather inexpensive modality [2]. Plunging ranula diagnosis is complicated...

SINCE the introduction of alpha-chymotrypsin (ACT) by Barraquer (1958a,b) as a zonulolytic agent to facilitate intracapsular cataract extraction, it has been widely used by surgeons in many countries. It is a proteolytic enzyme derived from the bovine pancreas, but its exact mechanism or mode of action is not clear.According to Barraquer it has specific action on the zonule and other structures...

PURPOSE The aim of this study was to demonstrate OK- 432 sclerotherapy efficacy for treatment of simple renal cysts. MATERIALS AND METHODS Twenty patients with 25 symptomatic or large simple cysts were treated by ultrasonography (US)-guided percutaneous aspiration and injection of OK-432 (8 men and 12 women, mean age 63.6 years, SD 9.5). Six patients presented with flank pain, 14 presented wi...