Tian, Jean Q., and Andrea Quaroni. Involvement of p21(WAF1/Cip1) and p27(Kip1) in intestinal epithelial cell differentiation. Am. J. Physiol. 276 (Cell Physiol. 45): C1245– C1258, 1999.—Using the conditionally immortalized human cell line tsFHI, we have investigated the role of cyclindependent kinase inhibitors (CKIs) in intestinal epithelial cell differentiation. Expression of cyclins, cyclin-...

Dobrian, Anca, Suzanne S. Wade, and Russell L. Prewitt. PDGF-A expression correlates with blood pressure and remodeling in 1K1C hypertensive rat arteries. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H2159–H2167, 1999.—We previously demonstrated remodeling of large and small arteries in angiotensin II-treated rats, paralleled by an increased expression of platelet-derived growth factor (PDGF)...

Meng, Xianzhong, Brian D. Shames, Edward J. Pulido, Daniel R. Meldrum, Lihua Ao, Kyung S. Joo, Alden H. Harken, and Anirban Banerjee. Adrenergic induction of bimodal myocardial protection: signal transduction and cardiac gene reprogramming. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1525–R1533, 1999.—This study tested the hypothesis that in vivo norepinephrine (NE) treatme...

Taylor, Ryan P., M. Brennan Harris, and Joseph W. Starnes. Acute exercise can improve cardioprotection without increasing heat shock protein content. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1098–H1102, 1999.—The aim of this study was to determine the effects of acute bouts of exercise on myocardial recovery after ischemia and heat shock protein expression. Adult female Sprague-Dawley ra...

Together with other Bristolians, most of whom are now out of uniform, I have been asked to record a few of my personal experiences while in the Army. Where should one begin ? The events of the last few years seem already far away. Like so many, I joined the forces and saw something of the world. Never have so many travelled so much and often, apparently, so much at random. Events crowd each oth...

trauma, degenerative changes, infection, and autoimmune disorders such as rheumatoid arthritis and ankylosing spondylitis. The perception and resultant reporting of this pain vary significantly according to cultural and social circumstances. Honeyman and Jacobs noted that Australian Aborigines significantly underreport pain and are rarely disabled by pain. Social circumstances also play an impo...

O’Connor, Timothy P., and Jared Diamond. Ontogeny of intestinal safety factors: lactase capacities and lactose loads. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R753–R765, 1999.—We measured intestinal safety factors (ratio of a physiological capacity to the load on it) for lactose digestion in developing rat pups. Specifically, we assessed the quantitative relationships bet...

Len, Wen-Bin, and Julie Y. H. Chan. Glutamatergic projection to RVLM mediates suppression of reflex bradycardia by parabrachial nucleus. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1482–H1492, 1999.—We investigated the role of glutamatergic projection from the parabrachial nucleus (PBN) complex to the rostral ventrolateral medulla (RVLM) in the PBN-induced suppression of reflex bradycardia ...

Monteith, Gregory R., and Mordecai P. Blaustein. Heterogeneity of mitochondrial matrix free Ca21: resolution of Ca21 dynamics in individual mitochondria in situ. Am. J. Physiol. 276 (Cell Physiol. 45): C1193–C1204, 1999.—The role of mitochondria in Ca21 homeostasis is controversial. We employed the Ca21-sensitive dye rhod 2 with novel, high temporal and spatial resolution imaging to evaluate ch...

Adams, G. R., S. A. McCue, M. Zeng, and K. M. Baldwin. Time course of myosin heavy chain transitions in neonatal rats: importance of innervation and thyroid state. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R954–R961, 1999.—During the postnatal period, rat limb muscles adapt to weight bearing via the replacement of embryonic (Emb) and neonatal (Neo) myosin heavy chains (MHC...