نتایج جستجو برای: 4b
تعداد نتایج: 4421 فیلتر نتایج به سال:
1. INTRODUCTION. For primes that can be written as a sum of integer squares, p = a 2 + (2b) 2 , Kaplansky [4] asked whether the binary quadratic form F = x 2 − py 2 always represents a and 4b (that is, are there integer solutions to x 2 − py 2 = a and x 2 − py 2 = 4b). Feit [1] and Mollin [4] proved that F does always represent a and 4b using the theory of ideals and the class group structure o...
Penicillium sp. WC-29-5 was co-cultured with Streptomyces fradiae 007 to produce five natural products (1-3, 4a and 4b) that were isolated and characterized by spectroscopic analysis. Interestingly, these compounds were found to be different from those produced in discrete fungal and bacterial controls. Among these compounds, the absolute configurations of compounds 4a and 4b were determined fo...
1. Postmitochondrial supernatants of rabbit reticulocyte lysates were chromatographed on heparin bound to Sepharose 4B, and the fraction retained on affinity columns was separated by subsequent gel filtration on Sepharose 4B into three fractions, two of them active in protein synthesis. 2. The heavier fraction sedimented at 40S and contained more than 10% RNA. This consisted predominantly of a ...
The major part of the gene inlB was sequenced in 24 strains of Listeria monocytogenes belonging to serovars 1/2a, 1/2b, 1/2c, 3b and 4b. A phylogenetic analysis based on the inlB nucleotide sequences showed that strains of serovars 1/2a and 1/2c were closely related, as well as those of serovars 1/2b and 3b. Strains sharing serovar 4b could be divided into two distinct groups. There were differ...
We have synthesized two alkenyl (C-6 and C-11 chains) pyrenes and one alkenyl (C-11 chain) perylene as the σ-π systems, which were electro-grafted on H-terminated Si surfaces to form the respective monolayers. The I-V characteristics of the monolayers revealed pronounced rectification in forward bias with a maximum rectification ratio (RR) of 2.5 × 10(5) at 2.5 V for the C-6-pyrene 4b, 1000 at ...
In primary visual cortex (V1) of macaque monkeys, motion selective cells form three parallel pathways. Two sets of direction selective cells, one in layer 4B, and the other in layer 6, send parallel direct outputs to area MT in the dorsal cortical stream. We show that these two outputs carry different types of spatial information. Direction selective cells in layer 4B have smaller receptive fie...
A series of genistein-polyamine conjugates (4a-4h) were designed, synthesized and evaluated as multi-functional anti-Alzheimer agents. The results showed that these compounds had significant cholinesterases (ChEs) inhibitory activity. Compound 4b exhibited the strongest inhibition to acetylcholinesterase (AChE) with an IC50 value of 2.75 μmol/L, which was better than that of rivastigmine (5.60 ...
A series of novel 4-(3-ethylphenyl)-1-substituted-4H-[1,2,4] triazolo[4,3-a]quinazolin-5-ones (4a-j) were synthesized by the cyclization of 3-(3-ethylphenyl)-2-hydrazino-3H-quinazolin-4-one (3) with various one-carbon donors. The starting material, compound 3, was synthesized from 3-ethyl aniline by a new innovative route with improved yield. When tested for their in vivo H1-antihistaminic acti...
The present work deals with the synthesis of some novel azo derivatives of dihydropyrimidinones. The structures of newly synthesized compounds were established on the basis of their FTIR, 1H NMR, Mass spectrometry and elemental analysis data results. The synthesized agents were assessed for their in vivo anti-inflammatory activity on the Wistar albino rats. The compounds were also screened for ...
Variants in cullin 4B (CUL4B) are a known cause of syndromic X-linked intellectual disability. Here, we describe an additional 25 patients from 11 families with variants in CUL4B. We identified nine different novel variants in these families and confirmed the pathogenicity of all nontruncating variants. Neuroimaging data, available for 15 patients, showed the presence of cerebral malformations ...
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