Rebecca Safran Q & A 5-methylcytosine. This specificity is unusual in fungi, but was predicted in prior studies of de novo methylation of repeated genes in C. cinerea. Recent attention has been focused on an additional modified base, 5-hydroxymethylcytosine, and its role in ‘poised chromatin’ in stem cells. The C. cinerea genome contains 38 copies of a gene predicted to carry out this conversio...

? ?????? ???????????? ?????????? ?????????? ????????? ????????? ?????????? ???? ??????? ? ????????? ?????????-??????????? ???????????? ??? 5-? ?????? ???????? ????????? ????????? ??????. ?????? ?????????? ?????????? ??????? ????????????? ????? ??????? ??????, ?????????-????????? ???? — ?? 23 ???????? ????????? ???????? 16 ??????????? (?? ????????? ????????? ?? ???), ?????????-????????? ????????...

Avoiding the problems inherent in retrospective assessment of pre-disaster health, Dirkzwager et al (pp. 144–149) found that pre-existing psychological problems were predictive of both self-report and general practitioner-recorded health problems (both psychological and physical) among survivors of a major explosion at a fireworks depot in The Netherlands. They also found poor post-disaster out...

In childhood ALL, an extra chromosome 5 is commonly encountered in cases with hyperdiploidy >50 chromosomes. The presence of trisomy 5 in high hyperdiploid childhood ALL is associated with a less favourable clinical outcome. Trisomy 5 as a sole abnormality in ALL is exceedingly rare and described in only 3 cases, including 2 adult ALL and 1 paediatrics case occurring in a 12-year old girl. Tris...