Background To investigate the effects of benzodiazepine receptor agonists on cognitive function in patients with chronic insomnia. Method According to history taking hypnotic drugs, they were divided into no medication group (n = 62), benzodiazepines 57) and non-benzodiazepines 53); all subjects The Pittsburgh Sleep Quality Scale, Epworth Insomnia Severity Index used evaluate their sleep qualit...

Nonhuman and human studies comparing the abuse liability of alprazolam to other commonly used benzodiazepines are reviewed. These studies are reviewed to determine to what extent prospective, controlled, experimental studies support opinions that alprazolam's abuse liability is greater than that of other commonly used benzodiazepines. Studies comparing the self-administration of alprazolam, the...

I report how some adulterants affect results for drugs of abuse in urine as measured by Roche RIA, Syva emit d.a.u., and Abbott TDx fpia (fluorescence polarization immunoassay) for the following drugs: amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, opiates, and phencyclidine (PCP). Sodium chloride interfered negatively with all of these drugs when assayed by emit and caused...

Abstract Introduction Sedative medications are commonly prescribed for older adults; these include neuroleptics, benzodiazepines, opioids, ‘z’ drugs and trazadone. The prevalence of sedative drug prescriptions is increasing (1). Nursing home residents three times more likely to be benzodiazepines (2). Regular medication review education have been shown reduce rates use in nursing homes (3). We ...

OBJECTIVE Benzodiazepines are frequently screened drugs in emergency toxicology, drugs of abuse testing, and in forensic cases. As the variations of benzodiazepines concentrations in biological samples during bleeding, postmortem changes, and redistribution could be biasing forensic medicine examinations, hence selecting a suitable sample and a validated accurate method is essential for the qua...