Introduction Phospholipases catalyse the cleavage of membrane phospholipids and thereby generate second messengers that participate in intracellular signal transduction processes or act as precursors of tissue hormones. Cytosolic phospholipase Az (cPLA2) is an 85 kDa enzyme that cleaves arachidonic acid at the sn-2 position of the phospholipid [1,2]. The intracellular location of the enzyme ena...

A new ascorbate-induced chloroplast absorbance change which has the characteristics of a carotenoid shift is described. The absorbance change was light-dependent at pH 7 but not at pH 5. The difference spectra for the light and dark changes were similar, showing a large absorbance peak at 505 nanometers, smaller peaks near 468 and 437 nanometers, and a sharp valley around 483 nanometers. The ab...

BACKGROUND To analyze setup deviations using daily megavoltage computed tomography (MVCT) and to evaluate three MVCT frequency reducing protocols for gynecologic cancer patients treated with helical tomotherapy. METHODS We recorded the setup errors of 56 patients with gynecological cancer observed throughout their whole course by matching their daily MVCT with the planning CT. Systematic and ...

OBJECTIVE CD4+ T cells from patients with active lupus have impaired ERK pathway signaling that decreases DNA methyltransferase expression, resulting in DNA demethylation, overexpression of immune genes, and autoimmunity. The ERK pathway defect is due to impaired phosphorylation of T(505) in the protein kinase Cδ (PKCδ) activation loop. However, the mechanisms that prevent PKCδ T(505) phospho...

We have studied the cytoskeletal association of intercellular adhesion molecule-1 (ICAM-1, CD54), an integral membrane protein that functions as a counterreceptor for leukocyte integrins (CD11/CD18). A linkage between ICAM-1 and cytoskeletal elements was suggested by studies showing a different ICAM-1 staining pattern for COS cells transfected with wild-type ICAM-1 or with an ICAM-1 construct t...

The study analyses the phonological interference of phoneme pronunciation [q] by Sundanese and Javanese speakers compared with Arabic speakers. researchers used a descriptive comparative qualitative method. listened, took notes, documented voice recordings male students from ethnic groups when reading Qur'an to collect research data analyse it using Praat software version 6.2.13. From results r...

Deliverable Title Catalogue of IoT Naming and Addressing Schemes in IERC Projects Revision Number V1.7 Deliverable Editor(s) John Soldatos (OpenIoT) Authors / Contributors Martin Bauer (IOT-A), Paul Chartier (CEN TC225), Klauss Moessner (IOT.est), Nechifor, Cosmin-Septimiu (iCore), Claudio Pastrone (ebbits), Josiane Xavier Parreira (GAMBAS), Richard Rees (CEN TC225), Domenico Rotondi (IoT@Work)...

Volker Vallon, Peer Wulff, Dan Yang Huang, Johannes Loffing, Harald Völkl, Dietmar Kuhl, and Florian Lang Departments of Medicine and Pharmacology, University of California, San Diego and Veterans Affairs Medical Center, San Diego, California; Department of Clinical Neurobiology, University of Heidelberg; Departments of Pharmacology and Physiology I, University of Tübingen; Department of Biolog...