Wyrok SN wskazuje na pojawianie się w polskiej praktyce kontraktowej nowych klauzul umownych we wzorcach umownych, które wydają gwaranci (banki i ubezpieczyciele ,art. 384 k.c.). Chodzi o klauzule, mogą służyć ochronie dłużnika (np. wykonawcy robot budowlanych, art. 647 k.c.) razie skorzystania przez wierzyciela (inwestora) z gwarancji „ pierwsze żądanie” bezpodstawnie tj. bez spełnienia warunk...

OBJECTIVE To identify demographic and clinical risk factors associated with mortality after initiation of antiretroviral therapy (ART) in a cohort of human immunodeficiency (HIV) infected children in KwaZulu-Natal, South Africa. METHODS We performed a retrospective cohort study of 537 children initiating antiretroviral therapy at McCord Hospital in KwaZulu-Natal, South Africa. Data were extra...

The TNF-receptor superfamily member CD30 is expressed on normal and malignant lymphocytes, including anaplastic large cell lymphoma (ALCL) cells. CD30 transmits multiple effects, including activation of NF-κB signaling, cell proliferation, growth arrest and apoptosis. How CD30 generates these pleiotropic effects is currently unknown. Herein we describe ALCL cells expressing truncated forms of t...

Vahşi hayvanların bir güç gösterisi bağlamında ve bu amaç için belirlenmiş özel alanlarda sergilenmesi avlanması hususunda ilk teşkil etmemekle birlikte Romalılar, diğer tüm antik uygarlıkları gölgede bırakan vahşi hayvan tüketimi ortaya koymuşlardır. Bu tüketim, geride bıraktığı katliamının çarpıcı boyutları itibarıyla uygarlıklardan ayrılmaktadır. Romalıların propaganda amacıyla gerçekleştird...

The yellow fluorescent protein phiYFPv (λem(max) ≃ 537 nm) with improved folding has been developed from the spectrally identical wild-type phiYFP found in the marine jellyfish Phialidium. The latter fluorescent protein is one of only two known cases of naturally occurring proteins that exhibit emission spectra in the yellow-orange range (535-555 nm). Here, the crystal structure of phiYFPv has ...

Recently, several studies have reported associations between fat mass and obesity-associated (FTO) gene mutations and cancer susceptibility. But little is known about their association with risk and survival of breast cancer in Chinese population. The aim of this study is to examine whether cancer-related FTO polymorphisms are associated with risk and survival of breast cancer and BMI levels in...

We defined the epitopes recognized by three influenza A virus-specific, H-2Kd-restricted CD8(+) cytotoxic T-lymphocyte (CTL) clones: H1-specific clone A-12, H2-specific clone F-4, and H1- and H2-cross-reactive clone B7-B7. The A-12 and B7-B7 clones recognized the same peptide, which comprises amino acids 533 to 541 (IYSTVASSL) of A/PR/8 hemagglutinin (HA). The F-4 and B7-B7 clones both recogniz...

A universal one-dose varicella vaccination program was introduced in 2005 in Republic of Korea. However, the incidence of varicella in Korea has tripled over the last decade. We conducted a community based 1:1 matched case-control study to assess the effectiveness of one MAV strain-based vaccine and three Oka strain-based vaccines licensed for use in Korea. All cases were children in Seoul, Kor...