Our study is the first report of exceptional Mycobacterium bovis strains that have some characteristics of M. tuberculosis. The strains were isolated from 8 patients living in Kazakhstan. While molecular markers were typical for M. bovis, growth characteristics and biochemical test results were intermediate between M. bovis and M. tuberculosis.

Babesia bovis and Cowdria ruminantium were identified for the first time in cattle on Unguja Island, Zanzibar. B bovis is common and widespread, although clinical disease had not been diagnosed previously. The vector of heartwater, Amblyomma variegatum, is found throughout Unguja but C ruminantium appears to be more localised in distribution than B bovis.

Streptococcus bovis is an uncommon cause of meningitis and subdural empyema. We report one case each of meningitis and subdural empyema in which S. bovis biotype II was isolated from both the spinal fluid and blood. In one case, the organisms were seen on a gram-stained preparation of cerebrospinal fluid. The first patient presented with gastrointestinal symptoms of unknown etiology, was immuno...

In the Netherlands, 1.4% of tuberculosis (TB) cases are caused by Mycobacterium bovis. After we admitted 3 patients with M. bovis infections to our reference hospital, we conducted a retrospective analysis of all M. bovis disease in the Netherlands during 1993-2007. We analyzed data from 231 patients for clinical, demographic, treatment, and outcome characteristics and for risk factors. Most pa...

Barnes, Isabel J. (Cornell University, Ithaca, N. Y.), H. W. Seeley, and P. J. VanDeMark. Nutrition of Streptococcus bovis in relation to dextran formation. J. Bacteriol. 82:85-93. 1961.-Three nutritional types of Streptococcus bovis were encountered. Minimal media for their growth are described. Transferable growth in defined media was always accompanied by dextran production and the nutrition...

The study was conducted to develop and evaluate an Indirect Hemagglutination Antibody Test (IHAT) for the serological diagnosis of Cysticercus bovis in live animals. IHAT was set-up inhouse and used to test serum samples of cattle against sheep red blood cell (SRBC) coated with crude extracts of C. bovis cyst. Serum samples for screening were collected from Addis Ababa abattoir (n=522), a dairy...

This study presents the results of a survey safety and protective efficacy candidate vector-based vaccine for bovine tuberculosis, using an influenza vector with NS1 mutation expressing M. bovis antigens ESAT-6 TB10.4. We vaccinated Balb/c outbred mice two times at 21 days apart. Our experimental design includes immunised or without adjuvant 15% Montanide Gel. The vaccine’s was determined by bi...

Mycobacterium bovis, the causative agent of bovine tuberculosis (bTB), is a multihost pathogen of public health and veterinary importance. We characterized the M. bovis isolated at the human-livestock-wildlife interface of the Serengeti ecosystem to determine the epidemiology and risk of cross-species transmission between interacting hosts species. DNA was extracted from mycobacterial cultures ...

SETTING Although animal models of aerosol inoculation of Mycobacterium tuberculosis and M. bovis have been reported using laboratory animals, a model of aerosol delivery of M. bovis to cattle has not been reported previously. OBJECTIVE Develop and characterize a model of aerosol delivery of M. bovis to cattle, and compare the distribution of lesions in cattle infected with either of two diffe...

The aim of this work was to determine the minimum infective dose of Mycobacterium bovis necessary to stimulate specific immune responses and generate pathology in cattle. Four groups of calves (20 animals) were infected by the intratracheal route with 1,000, 100, 10, or 1 CFU of M. bovis. Specific immune responses (gamma interferon [IFN-gamma] and interleukin-4 [IL-4] responses) to mycobacteria...