In the course of the prospective, randomized, double-blind trial the influence of a high-dose riboflavin substitution on the risk for preeclampsia was studied in a high-risk collective 1. The present contribution evaluates supplementary data from the already published PROPER trial. The patients were from the two study centers Mérida, Venezuela, and Moshi, Tanzania, they were randomized from the...

The purpose of this study was to evaluate whether maternal serum (MS) and amniotic fluid (AF) inhibin A levels are elevated in patients who subsequently develop severe preecalmpsia, and to investigate the correlation between MS and AF inhibin A levels in the second trimester. The study included 40 patients who subsequently developed severe preecalmpsia and 80 normal pregnant women. Inhibin A le...

background dynamic contrast-enhanced magnetic resonance imaging (dce - mri) has been widely used in the management of breast cancer, and its diagnostic value in breast imaging has been demonstrated. there have only been a few reports regarding the usefulness of pre-contrast imaging. knowledge about clinically significant findings of preoperative, pre-contrast t1 and t2 mr images will allow more...

First-trimester screening may be a major advantage over a second-trimester approach since it opens prospects for early and more efficient interventions. The aim of the current study was to evaluate whether the measurement of maternal serum inhibin A, activin A and placental growth factor (PlGF) at three to four months gestation with the second-trimester uterine artery pulsatility index (PI) are...

background: preeclampsia is a pregnancy multisystem disorder of unknown etiology. it is a significant cause of maternal and fetal morbidity and mortality. objectives: due to the significant role of magnesium in physiological regulation of blood pressure, this study was conducted to measure the level of magnesium in pre-eclampsia and control groups since the beginning of the pregnancy. materials...

clinical studies have shown that in pathological conditions such as endometriosis and reproductive tract infection (male and female) there is an activation status of macrophages that produce large quantities of nitric oxide (no) in addition to other effector molecules. large amounts of no may have embryotoxic roles and produce infertility. this study was designed to evaluate the effect of diffe...

background: full blood count has been shown to predict disease severity and mortality risk in cancer patients. this study aimed to highlight the degree of derangements of full blood count parameters and provide mean values in pre-chemotherapy breast cancer patients compared with apparently normal control subjects.methods: this was an unmatched case-control study among breast cancer patients att...

background: one of the most major obstacles of ovarian tissue vitrification is suboptimal developmental competence of follicles. matrix metalloproteinases 2 (mmp-2) and 9 (mmp-9) and their tissue inhibitors timp-1 and timp-2 are involved in the remodeling of the extracellular matrix in the ovaries. objective: this study aimed to evaluate the expression of mmp-2, mmp-9, timp-1, and timp-2 genes ...

introduction one of the most important pre-processing steps in optical coherence tomography (oct) is reducing speckle noise, resulting from multiple scattering of tissues, which degrades the quality of oct images. materials and methods the present study focused on speckle noise reduction and edge detection techniques. statistical filters with different masks and noise variances were applied on ...