Oxidant imbalance is one of the causative mechanisms of aluminum-induced neurotoxicity. In this study, we investigated aluminum-induced oxidant imbalance in non-neuronal tissues (liver, kidney and testis) and temporal cortex in rats. The differences in adaptations to superoxide and peroxide handling capacities (SPHC) of studied organs due to aluminum insult were also evaluated. Male Wistar rats...

There has been a plausible link between human exposure to aluminum and Alzheimer's disease for several decades. We contend that the only direct and ethically acceptable experimental test of the 'aluminum hypothesis', which would provide unequivocal data specific to the link, is to test the null hypothesis that a reduction in the body burden of aluminum to its lowest practical limit would have n...

To investigate the energy absorption characteristics and crush behavior of layered aluminum honeycomb, the experiments of layered aluminum honeycomb structure under quasi-static load had been carried out, mainly includes single, double, triple, four layer combinations. The results showed that: the peak force and the mean plateau force of single-layer aluminum honeycomb structure are proportiona...

Aluminum has been implicated in the etiology of the progressive dialytic encephalopathy. Data are presented on samples taken from patients on maintenance hemodialysis, during treatment. Aluminum was determined by electrothermal atomic absorption spectroscopy. Hemodialysis had no significant effect on serum aluminum concentrations, which ranged from 27 to 254 micrograms of Al per liter (1.00 to ...

This study evaluated different dosage forms of aluminum adjuvant in generating allergic rhinitis animal models. Forty female BALB/c mice were assigned to four groups, including three dosage forms of aluminum adjuvant [powder, gel, and hydrosolvent of aluminum hydroxide, Al(OH)3] mixed with ovalbumin to simulate the symptoms of allergic rhinitis and one control group. Although the aluminum adjuv...

We examined a simple screening method for judging the complex formation between a drug and aluminum(III) on a spot plate. As few drug had color reaction by basing on the binary complex formation of drug-aluminum(III), the ternary complex formation of drug-aluminum(III)-dye was studied this time using 50 kinds of drugs. The dyes used were Chromazurol S and Erythrosin. As a result, in the drug th...

thus humans are constantly exposed to this element. Little has been known about it’s metabolism and toxicity until the mid twentieth century. Aluminum is present in all tissues and organs in the body and when there is excessive accumulation multiple organ systems are effected by this metal (1). The important diseases induced by aluminum toxicity include dementia, anemia, myopathy, bone and join...

In addition, each capsule contains the following inactive ingredients: acetyltributyl citrate, ammoniomethacrylate copolymer-NF, D & C Red #28, D & C Yellow #10, D & C Yellow #10 Aluminum Lake, ethylcellulose, FD & C Blue #1 Aluminum Lake, FD & C Blue #2 Aluminum Lake, FD & C Red #40, FD & C Red #40 Aluminum Lake, gelatin-NF, magnesium stearate, methacrylic acid copolymer-NF, propylene glycol, ...

Multifocal osteonecrosis is a rare disease; chronic use of corticosteroids is considered the main risk factor. Patients with chronic renal failure can develop aluminum toxicity, which can lead to osteomalacia and encephalopathy. An association between osteonecrosis and aluminum toxicity has been reported among patients with dialytic renal insufficiency. Occupational exposure to aluminum rarely ...

Atmospheric inputs of sulfuric acid and nitric acid to noncalcareous higher-elevation watersheds in the White Mountain and Adirondack regions lead to comparatively high concentrations of dissolved aluminum in surface and ground waters. This phenomenon appears to result from modern increases in soil aluminum leaching. Transport of this aluminum to acidified lakes can lead to fish mortality. Comb...