BACKGROUND The optimal ablation strategy for persistent atrial fibrillation (AF) remains unclear. METHODS AND RESULTS This multicentre randomized study compared circumferential pulmonary vein ablation+linear ablation (control arm) versus circumferential pulmonary vein ablation+linear ablation+complex fractionated atrial electrogram (CFAE) ablation (CFAE arm) in patients with persistent AF. Ci...

BACKGROUND A common strategy for ablation of scar-based ventricular tachycardia is delivering multiple lesions in a linear pattern. METHODS AND RESULTS We tested the efficacy of a novel linear irrigated multipolar ablation catheter capable of creating linear lesions with a single application. Healthy swine underwent endocardial and epicardial linear ablation using a novel linear irrigated abl...

Atrial fibrillation (AF) ablation has evolved to the treatment of choice for patients with drug-resistant and symptomatic AF. Pulmonary vein isolation at the ostial or antral level usually is sufficient for treatment of true paroxysmal AF. For persistent AF ablation, drivers and perpetuators outside of the pulmonary veins are responsible for AF maintenance and have to be targeted to achieve sat...

Introduction: Radiofrequency ablation is an effective minimally invasive treatment for tumors. One primary source of difficulty is monitoring and controlling the ablation region. MR currently has a role in RF ablation due to its capability for temperature monitoring. RF ablation is typically performed at 480 kHz. If instead the ablation were to be performed at the Larmor frequency, then the MR ...

PURPOSE To investigate the efficacy and safety of percutaneous microwave ablation. METHODS Twenty-six rabbits with lung VX2 tumor were randomly divided into experimental and control group. In the experimental group, microwave ablation guided by ultrasound or CT was performed based on location of the tumor. Enhanced CT scan was carried out immediately before and after the ablation for all anim...

The influence of beam intensity on laser ablation quality and ablation size is experimentally studied on graphene-coated silicon/silicon dioxide substrates. With an amplified femtosecond-pulsed laser system, by systematically decreasing the average power, periodic stripes with decreasing widths are ablated. Histogram analyses of the untouched and ablated regions of scanning electron microscope ...

INTRODUCTION AND OBJECTIVES We report the results of the first Catheter Ablation Registry of the Arrhythmia Working Group of the Andalusian Society of Cardiology (AWGASC) for 2000. METHODS The register includes information about the ablation procedures performed in 2000, which was collected retrospectively and submitted voluntarily by four out of six cardiac electrophysiology laboratories of ...

The termination of atrial fibrillation (AF) by radiofrequency ablation in the left atrium is undeniable evidence that the pathophysiology underlying AF can be ameliorated. The cornerstone of this therapy, pulmonary vein isolation, can be achieved acutely in virtually 100% patients.1,2 Recurrent AF is the bane of this procedure, however, and is most commonly attributed to recovery of pulmonary v...

INTRODUCTION The aim of the study was to compare the success rate of an uptake-related ablation protocol in which the dose depends on an I-131 24-h neck uptake measurement and a fixed-dose ablation protocol in which the dose depends on tumour stage. METHODS All differentiated thyroid carcinoma patients with M0 disease who had undergone (near-) total thyroidectomy followed by I-131 ablation we...