Abstract Purpose The anaerobic digestion of the organic fraction municipal solid waste (OFMSW) is a treatment biologically optimizable. analysis microbial balance within digester allows not only to describe and improve efficiency system but also foresee potential variations after biochemical interventions. This work aims highlight methanogenic population in two similar parallel digesters identi...

Cannabinoids regulate biological processes governed by the hypothalamus including, but not limited to, energy homeostasis and reproduction. The present study sought to determine whether cannabinoids modulate A-type K(+) currents (I(A)) in neurons of the hypothalamic arcuate nucleus (ARC). Whole cell patch-clamp recordings were performed in slices through the ARC prepared from castrated female a...

R. Barona, B. Blossierb, P. Boucaudb, A. Deuzemanc, V. Drachd , F. Farchionie, V. Gimenez f , G. Herdoizag, K. Janseng, C. Michaelh, I. Montvayi, D. Palao f , E. Pallantec, O. Pèneb, S. Reker∗†c‡, C. Urbach j, M. Wagnerk and U. Wengerl aCEA, Centre de Saclay, IRFU/Service de Physique Nucléaire, F-91191 Gif-sur-Yvette, France bLaboratoire de Physique Théorique (Bât. 210), Université de Paris XI,...

Corynebacterium glutamicum, an established industrial amino acid producer, has been genetically modified for efficient succinate production from the renewable carbon source glucose under fully aerobic conditions in minimal medium. The initial deletion of the succinate dehydrogenase genes (sdhCAB) led to an accumulation of 4.7 g l(-1) (40 mM) succinate as well as high amounts of acetate (125 mM)...

Clinical use of antineoplastic drugs is associated with the development of numerous adverse effects that many patients find intolerable, including peripheral neuropathy. Cannabinoids have relieved neuropathic pain in different animal models. But their therapeutic activities could be affected by their psychoactive properties. The aim of this work was to determine the effect of cannabinoids in ci...

Background. The introduction of immunotherapy based on immune checkpoint inhibitors has significantly improve the effectiveness kidney cancer treatment. Nevertheless, not all patients respond to such treatment and there are no reliable predictive markers. Therefore, development a model system for assessing cellular response tumor seems be an urgent task. Aim. Development assess T-cell was focus...

BACKGROUND Achieving of moisture control especially gingival bleeding control is great challenge in clinical practice. Various hemostatic agents and techniques have been promoted for bleeding control during dental operation. But few studies have focused on the cytotoxicity of hemostatic solutions. AIM The aim of this study was to evaluate cytotoxic effect of hemostatic agents on human gingiva...

BACKGROUND Anandamide (AEA) is an endogenous lipid mediator that exerts several effects in the brain as well as in peripheral tissues. These effects are mediated mainly by two types of cannabinoid receptors, named CB(1)R and CB(2)R, making AEA a prominent member of the "endocannabinoid" family. Also immune cells express CB(1) and CB(2) receptors, and possess the whole machinery responsible for ...

Proteins induced by acid or base, during long-term aerobic or anaerobic growth in complex medium, were identified in Escherichia coli. Two-dimensional gel electrophoresis revealed pH-dependent induction of 18 proteins, nine of which were identified by N-terminal sequencing. At pH 9, tryptophan deaminase (TnaA) was induced to a high level, becoming one of the most abundant proteins observed. Tna...

Action potentials trigger synaptic terminals to synchronously release vesicles, but some vesicles release spontaneously. G-protein-coupled receptors (GPCRs) can modulate both of these processes. At cranial primary afferent terminals, the GPCR cannabinoid 1 (CB1) is often coexpressed with transient receptor potential vanilloid 1 (TRPV1), a nonselective cation channel present on most afferents. H...