This work reports, immobilization the Cobaloxime [Co (DH) Cl;DH,dimethylglyoximato)] onto the MCM- .The surface of MCM- was initially functionalized with -aminopropyltrimethoxysilane and -pyridine. For the electrostatic immobilization this was reacted with Cobaloxime and immobilization was achieved by an electrostatic interaction between the Co Cobaloxime and the N of the pyridine and NH amine....

1. Several species of micro-organisms that were capable of utilizing pyridine compounds as carbon and energy source were isolated from soil and sewage. Compounds degraded included pyridine and the three isomeric hydroxypyridines. 2. Suitable modifications of the cultural conditions led to the accumulation of pyridinediols (dihydroxypyridines), which were isolated and characterized. 3. Three spe...

The slope of plots of log k2 against the pKa of the leaving group for reactions of uncharged, monoanionic, and dianionic oxygen nucleophiles with three phosphorylated pyridine monoanions changes from PI, = -0.98 to -0.79 as the pK, of the oxygen nucleophile increases from 3.6 to 15.7 (aqueous solution; 25 "C; ionic strength, 1.5). This coupling between the strength of the nucleophile and the me...

In the search for new fluorescent triphenylamine (TP) derivatives, we studied influence of position and substitution diverse heterocyclic substituents. A library 10 triphenylamines bearing either oxazoles or thiazoles pyridiniums, substituted at different positions has been developed. The approach is based on a convergent C−H activation reaction between pyridine-oxazoles pyridine-thiazoles di-i...

1. Titration of haem with pyridine in alkaline media of low ionic strength yields a true pyridine haemochromogen, compound III, at very low concentrations of pyridine. 2. Graphical analysis of this titration gives the first spectrophotometric evidence for a dimeric haem. 3. Compound III is unstable and tends to aggregate to a second compound, compound II, whose formation is enhanced under those...

In the present study, a series of 2-(3'-substituted-2'-hydroxypropylamino)pyridines were synthesized and characterized by IR, 1H-NMR and elemental analysis. The compounds were investigated for anticonvulsant (150, 300 mg/kg) and cardiac activity. 2-(3'-Diethylamino-2'-hydroxypropylamino)pyridine 3 was found to exhibit the highest anticonvulsant activity. 2-(3'-Dimethylamino-2'-hydroxypropylamin...

Pyridine containing water clusters, H(+)(pyridine)(m)(H(2)O)(n), have been studied both experimentally by a quadrupole time-of-flight mass spectrometer and by quantum chemical calculations. In the experiments, H(+)(pyridine)(m)(H(2)O)(n) with m = 1-4 and n = 0-80 are observed. For the cluster distributions observed, there are no magic numbers, neither in the abundance spectra, nor in the evapor...

Dacarbazine is an antitumor prodrug which is used for the treatment of malignant metastatic melanoma and Hodgkin’s disease. It requires initial activation in liver through an N-demethylationreaction. The active metabolite prevents the progress of disease via alkylation of guanine bases in DNA strands. In order to investigate the importance of imidazole ring and its dynamictautomerization in ant...

The phenyltetrel pyridine-2-olates PhE(pyO)3 (E = Si, Ge, Sn; pyO pyridine-2-olate) were synthesized from the respective chlorides PhECl3 and 2-hydroxypyridine (2-pyridone) with aid of a sacrificial base (triethylamine). Their solid-state structures determined by single-crystal X-ray diffraction. PhSi(pyO)3 exhibits three-fold capped tetrahedral Si coordination sphere ([4+3]-coordination, Si···...