In the present study, a series of new hydrazone and sulfonamide derivatives of 1,2,4-triazole were synthesized. Initially three 4-substituted-5-(2-pyridyl)-1,2,4-triazole-3-thiones ZE-1(a-c) were treated with ethyl chloroacetate to get the corresponding thioesters ZE-2(a-c), which were reacted with hydrazine hydrate to the respective hydrazides ZE-3(a-c). The synthesized hydrazides were condens...

Hydrazines and their derivatives are versatile artificial and natural compounds that are metabolized by elusive biological systems. Here we identified microorganisms that assimilate hydrazones and isolated the yeast, Candida palmioleophila MK883. When cultured with adipic acid bis(ethylidene hydrazide) as the sole source of carbon, C. palmioleophila MK883 degraded hydrazones and accumulated adi...

In the title compound, C(7)H(8)N(2)O(4), the dihedral angle between the aromatic ring and the hydrazide grouping is 21.34 (7)°. In the crystal, the mol-ecules are linked into a three-dimensional network by O-H⋯O, O-H⋯N and N-H⋯O hydrogen bonds.

In the title compound, C(11)H(14)N(2)O(3), the planar hydrazide group is oriented with respect to the benzene ring at a dihedral angle of 48.00 (3)°. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds link the mol-ecules.

A series of S-glucosides 11a-14a and their benzamido derivatives 11b-14b have been synthesized by reacting D-glucose with thiol groups of 5-(2’-aminophenylene)-1,3,4-oxadiazole-2thioles 7(a,b), 5-(2’-aminophenylene)-1,3,4-thiadiazole-2-thiols 8(a,b), 5-(2’-aminophenylene)-1,2,4triazole-3-thiols 9(a,b) and 5-(2’-aminophenylene)-4-N-amino-1,2,4-triazole-3-thiols 10(a,b). The thiols 7(a,b)-10(a,b)...

Considerable evidence exists that the carboxyl-carbon atom of glycolic acid is the primary source of the CO(2) produced during photorespiration by leaves of many species of plants, including tobacco. Experiments were conducted to determine whether glyoxylate or glycine, both products of glycolic acid metabolism, is the more immediate precursor of photorespiratory CO(2).Illuminated tobacco leaf ...

The aim of present study was to design and synthesized a novel series compound which can be evaluate for anticonvulsant, anti-microbial activity. This derivatives Arylidene Hydrazides (4a-4k) were synthesised from o-chloro benzoic acid aniline via Ulmann reaction. synthetic method used simple, rapid economical found accurate reproducible. chemical reaction yielded as 11 Arylidiene Hydrazide acc...

A palladium-catalyzed desulfitative-denitrogenative conjugate addition of arylsulfonyl hydrazides to α,β-unsaturated ketones is described. The reaction showed very good selectivity and tolerated a wide range of functionalities under an atmosphere of oxygen with or without the aid of a metal co-oxidant.