Lithium (Li) doping is increasingly regarded as an effective modification for hydroxyapatite (HA) due to its excellent performances in osteogenesis. However, traditional method involving calcium, lithium and phosphorus salt (salt route) usually brought some unexpected ions, which could influence the properties of obtained materials largely. In present study, acid-base reaction (acid-base was ap...

The present study extends this analysis to the effects of drug modification on DNA, reovirus RNA, ribosomal RNA, and polyadenylic acid. The rate and extent of reaction of denatured DNA with the drug were found to be 2 to 3 times greater than with native DNA; a high ionic environment which is known to stabilize nucleic acid secondary structure decreased the rate and extent of nucleic acid modifi...