While the domestic cat has served as a mammalian model to study retinal circuitry from photoreceptors to ganglion cells, data on the visual capacities of large and endangered Felid species are sparse, We have gathered eyes from 7 felid species, cheetah (Acinonyx jubatus), lion (Panthera leo), tiger (Panthera tigris), jaguar (Panthera onca), Siberian manul (Felis manul), Eurasian lynx (Felis lyn...

An outbreak of anthrax in the Jwana Game Reserve in Jwaneng, Botswana, was first observed when three cheetahs (Acinonyx jubatus) died of the disease in November 2004. In the aftermath of this event, banked serum samples collected from 23 wild-caught cheetahs were examined, by the inhibition enzyme-linked immunoassay (ELISA), for antibodies to the protective antigen (PA) of Bacillus anthracis. O...

Alzheimer disease is a dementing disorder characterized pathologically by Aβ deposition, neurofibrillary tangles, and neuronal loss. Although aged animals of many species spontaneously develop Aβ deposits, only 2 species (chimpanzee and wolverine) have been reported to develop Aβ deposits and neurofibrillary tangles in the same individual. Here, the authors demonstrate the spontaneous occurrenc...