نتایج جستجو برای: activated thromboplastin time or aptt

تعداد نتایج: 4874188  

2013
Takenori Okada Yuji Takaekou Naomi Idei Norihiko Ohashi Shunichi Kaseda

Left atrial appendage (LAA) thrombosis is an important cause of cardiogenic cerebral thromboembolism. Apixaban is a member of the class of novel oral anticoagulants (NOAC) and is superior to warfarin in preventing stroke or systemic embolism, causes less bleeding, and results in lower mortality in patients with atrial fibrillation. There are few reports of resolution of LAA thrombus with other ...

Journal: :Hematology. American Society of Hematology. Education Program 2009
Ara Metjian Wendy Lim

A 35-year-old female presents with a prolonged activated partial thromboplastin time (aPTT) on routine testing, which is found to be due to a lupus anticoagulant. She has no medical issues, no personal or family history of thrombosis, no history of pregnancy loss, and no symptoms suggestive of an underlying rheumatologic disorder. She is a non-smoker and does not take oral contraceptives. You a...

Journal: :American journal of human genetics 2012
Weihong Tang Christine Schwienbacher Lorna M Lopez Yoav Ben-Shlomo Tiphaine Oudot-Mellakh Andrew D Johnson Nilesh J Samani Saonli Basu Martin Gögele Gail Davies Gordon D O Lowe David-Alexandre Tregouet Adrian Tan James S Pankow Albert Tenesa Daniel Levy Claudia B Volpato Ann Rumley Alan J Gow Cosetta Minelli John W G Yarnell David J Porteous John M Starr John Gallacher Eric Boerwinkle Peter M Visscher Peter P Pramstaller Mary Cushman Valur Emilsson Andrew S Plump Nena Matijevic Pierre-Emmanuel Morange Ian J Deary Andrew A Hicks Aaron R Folsom

Activated partial thromboplastin time (aPTT) and prothrombin time (PT) are clinical tests commonly used to screen for coagulation-factor deficiencies. One genome-wide association study (GWAS) has been reported previously for aPTT, but no GWAS has been reported for PT. We conducted a GWAS and meta-analysis to identify genetic loci for aPTT and PT. The GWAS for aPTT was conducted in 9,240 individ...

Journal: :Human & experimental toxicology 2012
Werner Cordier Allan D Cromarty Elsabie Botha Vanessa Steenkamp

The use of herbal preparations for staunching blood flow and reducing the risk of vascular thrombosis is common worldwide. In this study, aqueous and methanolic extracts of plants used to treat blood-associated complaints were investigated to determine their effects on red blood cell haemolysis and coagulation. The extent of haemolysis was determined spectrophotometrically. Prothrombin time (PT...

Journal: :Veterinary clinical pathology 2005
Melinda J Wilkerson Gary S Johnson Steve Stockham Lela Riley

A 1.5-year-old female Bichon Frise dog was evaluated for a life-threatening hemorrhagic condition that occurred after ovariohysterectomy, requiring 4 whole-blood transfusions. A hemostatic profile, including activated clotting time (ACT), one-stage prothrombin time (OSPT), activated partial thromboplastin time (APTT), buccal mucosal bleeding time, and specific assays (heat-precipitation microhe...

2012
Mark T Reding David L Cooper

BACKGROUND Bleeding symptoms commonly seen by multiple physician specialties may belie undiagnosed congenital or acquired bleeding disorders. Acquired hemophilia is a potentially life-threatening cause of unexplained acute bleeding manifested by an abnormal activated partial thromboplastin time (aPTT) that does not correct with 1:1 mixing with normal plasma. METHODS Practicing physicians (hem...

2006
T. DINEV H. HUBENOV L. LASHEV

The changes in blood coagulation parameters fibrinogen, thrombin time (TT), prothrombin time (PT) and activated partial thromboplastin time (APTT) were followed out after parenteral application of gentamicin (4 mg/kg), tobramycin (5 mg/kg), amikacin (10 mg/kg), kanamycin (10 mg/kg), apramycin (20 mg/kg) and spectinomycin (20 mg/kg) in goats for 5 days. Increased fibrinogen concentrations and re...

2018
Mauro Panigada Giacomo E Iapichino Matteo Brioni Giovanna Panarello Alessandro Protti Giacomo Grasselli Giovanna Occhipinti Cristina Novembrino Dario Consonni Antonio Arcadipane Luciano Gattinoni Antonio Pesenti

BACKGROUND There is no consensus on the management of anticoagulation during extracorporeal membrane oxygenation (ECMO). ECMO is currently burdened by a high rate of hemostatic complications, possibly associated with inadequate monitoring of heparin anticoagulation. This study aims to assess the safety and feasibility of an anticoagulation protocol for patients undergoing ECMO based on thromboe...

Journal: :Iranian Journal of Clinical Infectious Diseases 2021

Context: COVID-19 severe manifestations must be detected as soon possible. One of the essential poor characteristics is involvement coagulopathy. Simple coagulation parameters, including prothrombin time (PT), international normalized ratio (INR), activated partial thromboplastin (aPTT), and platelet, are widely accessible in many health centers. Objectives: This meta-analysis aimed to determin...

Journal: :JPMA. The Journal of the Pakistan Medical Association 1993
A N Shaikh M Khurshid

Patients with undiagnosed haemostatic defects seen at The Aga Khan Hospital and Fatimid Blood Transfusion Centre during the period of 7 years (1985-1992) were screened with routine tests including bleeding time (BT), whole blood clotting time (CT), platelet count, activated partial thromboplastin time (APTT), prothrombin time (PT) and 5 molar urea test. Nine patients had a positive 5 molar urea...

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