In vitro analysis of DNA in chromatin is often important for understanding mechanisms of regulation of transcription and other processes that occur on DNA. The basic unit of chromatin is the nucleosome core, containing two copies each of the core histones H2A, H2B, H3, and H4 to form a histone octamer that wraps 145 base pairs of DNA in a left-handed superhelix. In vivo, chromatin is associated...

Active vibration isolation is essential for a large range of high precision motion systems in industry. This paper aims to develop a framework for high performance robust vibration isolation by explicitly addressing multivariable flexible dynamical behavior. A framework is proposed that connects identification and control. In addition, a new data-driven uncertainty modeling procedure is used th...

Seismic isolation systems for buildings design are not as popular in the seismically active developing countries they developed ones. Several factors contribute to this, namely lack of knowledge on benefits seismic systems, unfamiliarity with procedure, and absence relevant building codes that provide guideline using system such countries. Recently, Indonesian code has been updated included str...

Hospitals use many strategies to control nosocomial transmission of vancomycin-resistant enterococci (VRE). Strategies include "passive surveillance," with isolation of patients with known previous or current VRE colonization or infection, and "active surveillance," which uses admission cultures, with subsequent isolation of patients who are found to be colonized with VRE. We created a mathemat...

We have obtained precatalytic (enzyme-substrate complex) and postcatalytic (enzyme-product complex) crystal structures of an active full-length hammerhead RNA that cleaves in the crystal. Using the natural satellite tobacco ringspot virus hammerhead RNA sequence, the self-cleavage reaction was modulated by substituting the general base of the ribozyme, G12, with A12, a purine variant with a muc...