It is possible that some of the systemic responses to sub-acute ruminal acidosis (SARA) may be caused by increased intestinal starch fermentation. The objective this experiment was evaluate effect abomasal infusion up 3 g/kg body weight corn (approximately 1.6 kg starch/d) on fecal measures fermentation, plasma acute phase proteins, and white blood cell populations. Six ruminally cannulated cow...

Metabolic acidosis is a condition often induced by ruminal acidosis. Identification of the specific proteolytic pathways affected by metabolic acidosis and characterization of AA concentration changes induced by metabolic acidosis in ruminants has yet to be confirmed. The objective of this study was to examine the effect of nutritionally induced metabolic acidosis on lamb plasma AA and tissue v...

3-Methylindole, a ruminal fermentation product of tryptophan, induces acute pulmonary edema and emphysema in cattle, and 3-methylindole is present in the ruminal fluid and blood of cows with a natually occurring form of this disease. Monensin, a polyether antibiotic and widely used feed additive for beef cattle, prevented tryptophan-induced acute bovine pulmonary edema and emphysema. Monensin a...

Although acidosis has long been known to cause vasodilation in certain systemic vascular beds (13), its effect on the pulmonary vessels remains unsettled. This uncertainty stems from the inconsistent effects of an acute change in blood pH on the pulmonary circulation of the isolated lung (4-8) and of the lung perfused in situ (9), and the lack of observations on intact animals and man. Liljestr...

Four crossbred wethers were utilized in a randomized block design to test Thiopeptin, an antibiotic, at .25% of the amount of wheat given, two levels of NaHCO3 (2 and 4%) expressed as a percentage of the wheat given, and a combination of the Thiopeptin (.25%) plus 2% NaHCO3. Acidosis was induced in the four sheep (controls) by feeding cracked soft white wheat at 50 g/kgBW -Ts divided among thre...

Background: Ethylene glycol is a toxic alcohol which is used in brake fluid, antifreeze, coolants, preservatives and chemical solvents. Ethylene glycol poisoning usually results in depression of the central nervous system, renal insufficiency and cardiopulmonary compromise, while laboratory findings include metabolic acidosis, increased anion gap, increased osmolar gap and calcium oxalate cryst...