نتایج جستجو برای: acute ischemia stroke
تعداد نتایج: 660793 فیلتر نتایج به سال:
The main challenge of stroke research is to translate promising experimental findings from the bench to the bedside. Many suggestions have been made how to achieve this goal, identifying the need for appropriate experimental animal models as one key issue. We here discuss the macrosphere model of focal cerebral ischemia in the rat, which closely resembles the pathophysiology of human stroke bot...
conclusions the effect of diabetes mellitus on stroke was more significant than on ihd, and the effect of high ldl-c level was more significant on ihd than on stroke, other risk factors, including hypertension, have similar rrs for ihd and stroke. health care professionals need more training regarding the rrs of these risk factors in the iranian society, and health decision makers should consid...
background: acute coronary syndrome is a life-threatening condition. considerable doubts exist over the effects of this disease on patients’ quality of life. the aim of this study was to survey quality of life and its influencing factors in patients with acute coronary syndrome. methods: a convenience sample of 300 patients with acute coronary syndrome was drawn from shahid beheshti hospital, k...
Ischemic stroke is the second leading cause of death worldwide. Only one moderately effective therapy exists, albeit with contraindications that exclude 90% of the patients. This medical need contrasts with a high failure rate of more than 1,000 pre-clinical drug candidates for stroke therapies. Thus, there is a need for translatable mechanisms of neuroprotection and more rigid thresholds of re...
Dopamine and norepinephrine fluorescence in the nucleus caudatus and putamen and cerebral cortex was markedly depleted along with rCBF reduction in symptomatic stroke-prone spontaneously hypertensive rats (SHRSP) with bilateral carotid artery ligatioa under light pentobarbital anesthesia. An accumulation of fluorescence at the intima of blood Teasels, especially in the nucleus caudatus and puta...
OBJECTIVE Acute coronary syndromes and ischemic cerebral stroke share similarities regarding elevated platelet activation. In coronary syndromes, the importance of inflammation with platelet-leukocyte interaction has been demonstrated. Recent infection is an established risk factor for ischemic stroke; the role of platelet-leukocyte interaction in these patients had not been investigated. MET...
ischemic stroke accounts for about 87 percent of all cases. it occurs as a result of an obstruction within a vessel of the brain and sudden loss of blood circulation to the corresponding area resulting in the loss of brain function. it is caused by thrombotic or embolic occlusion of an artery and is more common than hemorrhagic stroke. we know that most of the injuries after an acute ischemic s...
BACKGROUND AND PURPOSE The neuroprotective potential of citicoline in acute ischemic stroke has been shown in many experimental studies and, although the exact mechanisms are still unknown, a clinical Phase III trial is currently underway. Our present study was designed to check whether citicoline also enhances neuroregeneration after experimental stroke. METHODS Forty Wistar rats were subjec...
Background: Dimethyl sulfoxide (DMSO) has been used as a solvent for many drugs in ischemic experiments. DMSO has many biological benefits, including antioxidant, anti-inflammatory, platelet aggregation inhibiting and cell membrane stabilizing effects. Moreover, some experimental studies report that DMSO has a neurprotective effect in permanent focal cerebral ischemia. Despite the effect of DMS...
acute paraplegia is a rare but catastrophic complication of surgeries performed on aorta and corrective operations of vertebral column. trauma to spinal cord after spinal anesthesia and ischemia of spinal cord also may lead to acute paraplegia. acute paraplegia as a complication of general anesthesia in surgeries performed on sites other than aorta and vertebral column is very rare. here we pre...
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