Liver dysfunction is one of the most recognized complications in patients with acute heart failure (HF) and therefore a liver function score may be useful for risk-stratification those patients. Recently, albumin-bilirubin (ALBI) was developed as new model to assess disease. We explored association between ALBI at admission in-hospital mortality HF.

Severe clinical course of acute renal and acute liver failure is recognized as life-threatening condition, often developing in critically ill patients, demanding intensive care. Continuous renal replacement techniques, including venovenous hemodialysis/hemofiltration/hemodiafiltration/ultrafiltration (CWHD/CWHF/CWHDF/SCUF) are becoming the therapeutic modality of choice in unstable patients wit...

M l T p c s e m t e a a s s b c o s c p nd-stage liver disease is the tenth most frequent cause f death in the US, causing approximately 25,000 deaths nnually. Although only about 2,000 cases of acute liver ailure occur each year in the US, the mortality rate emains as high as 28%. The application of orthotopic iver transplantation to acute and fulminant hepatic failre has increased the surviva...

We present a patient with no medical history admitted for jaundice and dark coloured urine. Further investigations revealed hepatitis A related acute liver failure while the patient had no travel history, nor contact with infected individuals. After admission, the patient deteriorated fulfilling the King's College criteria for acute liver failure. Two days after admission, he underwent liver tr...

The advent of successful orthotopic liver transplantation for patients with both acute and chronic liver failure has been a major breakthrough in clinical practice, for patients who would have otherwise died [1]. Patients with chronic liver disease are now listed for transplantation well before terminal liver failure, and therefore can potentially wait for a suitable donor liver. However, those...

This study investigated features and clinical implications of HBV mutations in patients with different clinical manifestations. In total, 516 patients were enrolled in this study, including 131 patients with acute hepatitis B, 239 patients with chronic hepatitis B, and 146 patients with acute-on-chronic liver failure. HBV genotypes and mutations were analyzed by direct sequencing of complete vi...