نتایج جستجو برای: acute myeloid leukaemia
تعداد نتایج: 531781 فیلتر نتایج به سال:
1. Balgobind BV, Hollink IH, Arentsen-Peters ST, et al. Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia. Haematologica. 2011;96(10):1478-1487. 2. Pession A, Rondelli R, Basso G, et al. AML Strategy & Study Committee of the Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP). Treatment and long-term r...
Background: Aberrant expression of cross-lineage antigens gives valuable insight into the diagnosis and prognosis of acute leukemia. In countries like India, cytogenetic tests are widely accessible. Exploring the prognostic value of an accessible test is of great importance. Therefore, establishing a population-specific immunophenotype database will enable to design an antibody panel equipped t...
Recently, whole genome sequencing approaches have pinpointed mutations in genes that were previously not associated with cancer. For Acute Myeloid Leukaemia (AML), and other myeloid disorders, these approaches revealed a high prevalence of mutations in genes encoding the chromosome cohesion complex, cohesin. Cohesin mutations represent a novel genetic pathway for AML, but how AML arises from th...
dL, total bilirubin 2.34 mg/dL, LDH 4 077 U/L. Brain CTscan: right frontal and right cerebellar hematomas. Bone marrow smear presented 89% of myeloperoxidase-positive blast cells, consistent with an acute myelomonocytic leukaemia (Fig. 2). Immunophenotypic analysis showed 60% of monocyte-derived dendritic cells, compatible with an aggressive and rare form of leukemia – acute myeloid dendritic c...
simultaneous proptosis and facial palsy as the clinical presentation of childhood acute myeloid leukaemia (aml) is very rare. to date, no case have been reported anywhere to the best of our knowledge. extra medullary leukemic deposits or granulocytic sarcoma (gs) is a rare manifestation in about 3% of childhood aml, 9.3% of gs manifested as orbit deposits causing proptosis in one or both eyes. ...
CCAAT/enhancer-binding protein alpha (C/EBPα) is an essential transcription factor for myeloid lineage commitment. Here we demonstrate that acetylation of C/EBPα at lysine residues K298 and K302, mediated at least in part by general control non-derepressible 5 (GCN5), impairs C/EBPα DNA-binding ability and modulates C/EBPα transcriptional activity. Acetylated C/EBPα is enriched in human myeloid...
REFERENCES 1. Zagaria A, Anelli L, Coccaro N, et al. 5'RUNX1-3'USP42 chimeric gene in acute myeloid leukemia can occur through an insertion mechanism rather than translocation and may be mediated by genomic segmental duplications. Mol Cytogenet 2014;7:66. 2. Masetti R, Togni M, Astolfi A, et al. Whole transcriptome sequencing of a paediatric case of de novo acute myeloid leukaemia with del(5q) ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید