CONTEXT The incidence of lymphocele after renal transplantation varies between 0.6 and 18% of cases, and many factors have been associated to its etiology. Cellular rejection of the kidney allograft has been described as a possible causal factor of lymphocele. OBJECTIVE To analyze the possible relationship between lymphocele and acute cellular rejection. DESIGN A retrospective study. SETT...

Introduction: Use of marginal kidneys, such as from non-heart beating donors (NHBD), offers the opportunity to compensate for the growing discrepancy for demand for kidneys and their availability from brain-stem dead donors. Such kidneys are prone to delayed graft function (DGF), which can be prolonged by nephrotoxic drugs including calcineurin inhibitors. This study aims to determine whether u...

A short cold ischemic time, an optimal HLA match and other pre-transplant factors are in a key role in the success of kidney transplantation. Over the past decades, the acute rejection rate of kidney transplants has fallen dramatically and the 1-year graft survival rate has increased to 90% in transplantations with deceased donors and 95% with living related donors. This increase in graft survi...

Background and Objective: Due to the importance of acute kidney injury associated in patients with sepsis and the impact of various factors on mortality and hospital stay of these patients, this study was conducted to investigate the clinical features and risk factors for acute kidney injury in patients with sepsis. In addition, we examined whether the severity of acute kidney injury affected c...

OBJECTIVE  To determine the pattern of histopathology in living-related, kidney transplant recipients (KTRs) from a centre Khyber Pakhtunkhwa (KPK), Pakistan. STUDY DESIGN Descriptive, observational study. PLACE AND DURATION OF Institute Kidney Diseases, Peshawar, August 2008 to July 2018. METHODOLOGY A retrospective review graft biopsy reports and clinical charts was carried out. Allograft bio...

background: thymoglobuline (tg), is used for both induction and rejection therapy in kidney transplantation (tx). this study was conducted to compare between adding tg or not to the conventional drugs to evaluate the rate of rejections, infections and costs. methods: in two groups of patients, each of 45 cases group a received conventional drugs (cyclosporine, mycophenolate and prednisolone) an...

Since the first successful operation in man in 1954, kidney transplantation has evolved from an experimental therapy to the treatment of choice for patients with end-stage renal disease (ESRD). Kidney transplantation offers a significant survival benefit to patients suffering from ESRD and improves their quality of life as compared with patients who remain dependent on dialysis. In children, ki...

background and aim the most common complication of renal transplantation is allograft dysfunction, which in some cases leads to graft loss. the role of graft nephrectomy in the management of transplant failure is controversial. the procedure remains associated with a significant morbidity and also mortality. our main purpose was the comparison between clinical and pathological diagnosis of graf...

OBJECTIVES Antibody-mediated rejection after kidney transplant is less responsive to conventional antirejection therapies. The proteasome inhibitor bortezomib has activity against mature plasma cells that produce damaging donor-specific antibodies. We present our experience of using a bortezomib-based regimen in patients with severe antibody-mediated rejection. MATERIALS AND METHODS A retrosp...